37 Result(s)

Article

Glucose and HODEs regulate Aspergillus ochraceus quorum sensing through the GprC-AcyA pathway

Aspergillus ochraceus is the traditional ochratoxin A (OTA)-producing fungus with density-dependent behaviors, which is known as quorum sensing (QS) that is mediated by signaling molecules. Individual cells trend...

**g Gao, Huiqing Liu, Yuxin **, Yunbo Luo… in Cellular and Molecular Life Sciences (2024)

Article

When DNA-damage responses meet innate and adaptive immunity

When cells proliferate, stress on DNA replication or exposure to endogenous or external insults frequently results in DNA damage. DNA-Damage Response (DDR) networks are complex signaling pathways used by multi...

Jie Tong, Jiangwei Song, Wuchao Zhang, **gbo Zhai… in Cellular and Molecular Life Sciences (2024)

Article

Analysis of clinical features and risk factors of peripheral neuropathy in patients with primary Sjögren's syndrome

To observe the clinical features and efficacy of immunosuppressive therapy in patients with primary Sjögren's syndrome (PSS) combined with peripheral neuropathy (PN) syndrome and to explore the risk factors fo...

Zhihong Wu, Dong Wang, Lirong Chen, Kaipu **anyu… in European Journal of Medical Research (2023)

Article

Results of the phase IIa study to evaluate the efficacy and safety of rezivertinib (BPI-7711) for the first-line treatment of locally advanced or metastatic/recurrent NSCLC patients with EGFR mutation from a phase I/IIa study

Rezivertinib (BPI-7711) is a novel third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). This phase IIa study was part of a phase I/IIa study (NCT03386955), aimed to evaluat...

Yuankai Shi, Jianying Zhou, Yanqiu Zhao, Bo Zhu, Liangming Zhang, **ngya Li… in BMC Medicine (2023)

Article

Silencing TRAIP suppresses cell proliferation and migration/invasion of triple negative breast cancer via RB-E2F signaling and EMT

TRAIP, as a 53 kDa E3 ubiquitin protein ligase, is involved in various cellular processes and closely related to the occurrence and development of tumors. At present, few studies on the relationship between TR...

Yan Zheng, Huiqing Jia, ** Wang, Litong Liu, Zhaoxv Chen… in Cancer Gene Therapy (2023)

Article

Changes in the BTK/NF-κB signaling pathway and related cytokines in different stages of neuromyelitis optica spectrum disorders

Neuromyelitis optica spectrum disorders (NMOSDs) are blindness-causing neuritis; their pathogenesis is still not fully elucidated. Although it has been determined that Bruton tyrosine kinase (BTK) and NF-κB ar...

Huimin Qiao, Zhuofeng Mao, Wei Wang, **n Chen… in European Journal of Medical Research (2022)

Article

Efficacy of transcutaneous electrical nerve stimulation in people with pain after spinal cord injury: a meta-analysis

Meta-analysis.

Ye Yang, Yun Tang, Huiqing Qin, Jianwen Xu in Spinal Cord (2022)

Article

Multi-parametric MRI phenotype with trustworthy machine learning for differentiating CNS demyelinating diseases

Misdiagnosis of multiple sclerosis (MS) and neuromyelitis optica (NMO) may delay the treatment, resulting in poor prognosis. However, the precise identification of these two diseases is still challenging in cl...

**g Huang, Bowen **n, **uying Wang, Zhigang Qi… in Journal of Translational Medicine (2021)

Article

Fludarabine inhibits type I interferon-induced expression of the SARS-CoV-2 receptor angiotensin-converting enzyme 2

Huiqing **u, Jiali Gong, Tiancha Huang, Yanmei Peng… in Cellular & Molecular Immunology (2021)

Article

Plasma extracellular vesicle delivery of miR-210-3p by targeting ATG7 to promote sepsis-induced acute lung injury by regulating autophagy and activating inflammation

Extracellular vesicles (EVs) can be used for intercellular communication by facilitating the transfer of miRNAs from one cell to a recipient cell. MicroRNA (miR)-210-3p is released into the blood during sepsis...

Guang Li, Bo Wang, **angchao Ding, **nghua Zhang… in Experimental & Molecular Medicine (2021)

Article

The fecal microbiota of patients with pancreatic ductal adenocarcinoma and autoimmune pancreatitis characterized by metagenomic sequencing

The fecal microbiota in pancreatic ductal adenocarcinoma (PDAC) and in autoimmune pancreatitis (AIP) patients remains largely unknown. We aimed to characterize the fecal microbiota in patients with PDAC and AI...

Wenli Zhou, De Zhang, Zhengpeng Li, Huiqing Jiang… in Journal of Translational Medicine (2021)

Article

The acupoint herbal plaster for the prevention and treatment of postoperative nausea and vomiting after PLIF with general anesthesia: study protocol for a multicenter randomized controlled trial

Postoperative nausea and vomiting (PONV) are common in posterior lumbar intervertebral fusion (PLIF) patients undergoing general anesthesia. The previous clinical observation has shown that a traditional acupo...

Huiqing Xu, Xu Wei, Ranxing Zhang, Ling Li, Zhijun Zhang, Ruo Jia, **aofei Zhang… in Trials (2021)

Article

Effect of early prophylactic low-dose recombinant human erythropoietin on retinopathy of prematurity in very preterm infants

Very preterm infants are at risk of develo** retinopathy of prematurity (ROP). Recombinant human erythropoietin (rhEPO) is routinely used to prevent anemia in preterm infants; however, the effect of rhEPO on...

Huiqing Sun, Juan Song, Wenqing Kang, Yong Wang… in Journal of Translational Medicine (2020)

Article

Erythropoietin prevents necrotizing enterocolitis in very preterm infants: a randomized controlled trial

Necrotizing enterocolitis (NEC) is one of the most severe complications in very preterm infants, but there are currently no accepted methods to prevent NEC. Studies have shown that erythropoietin (EPO) has the...

Yong Wang, Juan Song, Huiqing Sun, Falin Xu, Kenan Li… in Journal of Translational Medicine (2020)