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Article
Aerosol injection in soft soils: permeability enhancement by fractures
In our recent paper, we reported the development and application of the aerosol injection technique to accelerate the consolidation in soft soils. Aerosol injection technique is a process that involves injecti...
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Article
Navβ2 Intracellular Fragments Contribute to Aβ1-42-Induced Cognitive Impairment and Synaptic Deficit Through Transcriptional Suppression of BDNF
A pathological hallmark of Alzheimer’s disease (AD) is the region-specific accumulation of the amyloid-beta protein (Aβ), which triggers aberrant neuronal excitability, synaptic impairment, and progressive cog...
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Article
Single-cell transcriptomics across 2,534 microbial species reveals functional heterogeneity in the rumen microbiome
Deciphering the activity of individual microbes within complex communities and environments remains a challenge. Here we describe the development of microbiome single-cell transcriptomics using droplet-based s...
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Article
Open AccessA new strategy for fabricating low haze p-type CuI film
As an intrinsic p-type transparent conductor with a wide band gap of 3.1 eV, γ-CuI full of potential has gradually attracted the attention of researchers. However, γ-CuI films deposited by various techniques g...
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Article
Estimation of Extreme Value Distribution and Probability of Minor Failures in Rockfill Dam Response to Non-Stationary Seismic Excitation
To address the problem of the small failure probability of highly reliable structures such as rockfill dams, marine platforms and super high-rise buildings, in this paper, a method to estimate the extreme valu...
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Article
Association Between a Failed Prominence Eruption and the Drainage of Mass from Another Prominence
Sympathetic eruptions of solar prominences have been studied for decades, however, it is usually difficult to identify their causal links. Here, we present two failed prominence eruptions on 26 October 2022 an...
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Article
Disruption of DNA-PKcs-mediated cGAS retention on damaged chromatin potentiates DNA damage-inducing agent-induced anti-multiple myeloma activity
Targeting DNA damage repair factors, such as DNA-dependent protein kinase catalytic subunit (DNA-PKcs), may offer an opportunity for effective treatment of multiple myeloma (MM). In combination with DNA damage...
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Article
Open AccessCu(II)-based complex loaded with drug paclitaxel hydrogels against thyroid cancer and optimizing novel derivatives
This study introduces a novel approach for synthesizing a Cu(II)-based coordination polymer (CP), {[Cu(L)(4,4´-OBA)]·H2O}n (1), using a mixed ligand method. The CP was successfully prepared by reacting Cu(NO3)2·3...
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Article
A widely used nonionic surfactant with desired functional groups as aqueous electrolyte additives for stabilizing Zn anode
Aqueous Zn-ion batteries (AZIBs) have emerged as potential candidates for Li-ion batteries due to their intrinsic safety and high capacity. However, metallic Zn anodes encounter dendrite growth and water-induc...
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Article
Open AccessIntrauterine chilled saline instillation reduces endometrial impairment on MRI after ultrasound-guided percutaneous microwave ablation of uterine adenomyosis
To investigate whether intrauterine chilled saline can reduce endometrial impairment during US-guided percutaneous microwave ablation (PMWA) of adenomyosis.
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Article
Advancements of Macrophages Involvement in Pathological Progression of Colitis-Associated Colorectal Cancer and Associated Pharmacological Interventions
Intestinal macrophages play crucial roles in both intestinal inflammation and immune homeostasis. They can adopt two distinct phenotypes, primarily determined by environmental cues. These phenotypes encompass ...
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Article
Application of UiO-66 and its composites for remediation and resource recovery of typical environmental contaminants: a review
UiO-66 series metal–organic framework materials (MOFs) are typical porous materials assembled by Zr4+ with a large mass-to-nucleus ratio and terephthalic acid ligands, which form tetrahedral and octahedral cages ...
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Article
Efficacy of chidamide maintenance therapy versus autologous stem cell transplantation versus observation as a post-remission choice in the survival of adult patients with peripheral T-cell lymphoma: Post hoc analysis of a prospective, multicenter, phase 2 study in China
In this prospective, multicenter, Phase 2 clinical trial (NCT02987244), patients with peripheral T-cell lymphomas (PTCLs) who had responded to first-line chemotherapy with cyclophosphamide, doxorubicin or epir...
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Article
Simplified Calculation of Earthquake Energy Transfer of Different Pipe Supports Inside Utility Tunnel at Horizontal Non-Homogeneous Field
A buried utility tunnel can effectively protect internal pipes by preventing or mitigating corrosion, external damage, and facilitating maintenance. During an earthquake, the energy from seismic waves is trans...
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Article
Open AccessBrachytherapy in craniopharyngiomas: a systematic review and meta-analysis of long-term follow-up
Brachytherapy has been indicated as an alternative option for treating cystic craniopharyngiomas (CPs). The potential benefits of brachytherapy for CPs have not yet been clarified. The purpose of this work was...
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Article
MDM2 accelerated renal senescence via ubiquitination and degradation of HDAC1
Senescence, an intricate and inevitable biological process, characterized by the gradual loss of homeostasis and declining organ functions. The pathological features of cellular senescence, including cell cycl...
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Article
Unlocking the Potential of Poly(butylene succinate) through Incorporation of Vitrimeric Network Based on Dynamic Imine Bonds
Poly(butylene succinate) (PBS) exhibits many advantages, such as renewability, biodegradability, and impressive thermal and mechanical properties, but is limited by the low melt viscosity and strength resulted...
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Article
Open AccessSustainable upcycling of mixed spent cathodes to a high-voltage polyanionic cathode material
Sustainable battery recycling is essential for achieving resource conservation and alleviating environmental issues. Many open/closed-loop strategies for critical metal recycling or direct recovery aim at a si...
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Article
Investigations of the photoelectrochemical and photo-Fenton properties of TiO2/FeOCl nanocomposites
The TiO2/FeOCl composites were prepared by a simple calcination method, and the photo-Fenton performance of the TiO2/FeOCl photo-Fenton catalysts was investigated for the degradation of Rhodamine B (RhB) and Tetr...
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Article
Open AccessDynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance
Although DHFR gene amplification has long been known as a major mechanism for methotrexate (MTX) resistance in cancer, the early changes and detailed development of the resistance are not yet fully understood.
