4,899 Result(s)
within
Hui-**g Li
-
Article
Open AccessATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8+ T cells
Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...
-
Article
Navβ2 Intracellular Fragments Contribute to Aβ1-42-Induced Cognitive Impairment and Synaptic Deficit Through Transcriptional Suppression of BDNF
A pathological hallmark of Alzheimer’s disease (AD) is the region-specific accumulation of the amyloid-beta protein (Aβ), which triggers aberrant neuronal excitability, synaptic impairment, and progressive cog...
-
Article
Mutual correlation and butterfly effect of charged Reissner-Nordström AdS black hole with quintessence
In this article, based on shock geometry and chaos theory, we mainly study the butterfly effect of the Reissner-Nordström AdS black hole (RN-AdS black hole) with quintessence by the method of mutual correlatio...
-
Article
Activation of 5-HT6 Receptors in the Ventrolateral Orbital Cortex Produces Anti-Anxiodepressive Effects in a Rat Model of Neuropathic Pain
The comorbidity of anxiety and depression frequently occurs in patients with neuropathic pain. The ventrolateral orbital cortex (VLO) plays a critical role in mediating neuropathic pain and anxiodepression in ...
-
Article
Assessment of environmental and biological stress using mitochondria-targeted red-emitting and near-infrared fluorescent probes for biothiol analysis: a review
Levels of biological thiols, or “biothiols,” in mitochondria can be used to assess environmental and biological oxidative stress, which can cause health issues such as malignant tumors and neurological disease...
-
Article
Revealing interaction of pyridinic N in N-doped carbon with Sn sites for improved CO2 reduction
N-doped carbon (NC) materials have emerged as attractive supports for metal-based catalysts, enhancing their catalytic performance through the metal–support interactions. However, gaining fundamental insights ...
-
Article
Open AccessAssociation of early-term birth and breastfeeding practices with nutritional outcomes in singleton term infants: a multicenter cross-sectional study
Limited research has explored the associations of gestational age (GA) and breastfeeding practices with growth and nutrition in term infants.
-
Article
Open AccessNeuropeptide natalisin regulates reproductive behaviors in Spodoptera frugiperda
Natalisin (NTL) is a conserved neuropeptide, only present in insects, that has been reported to regulate their sexual activity. In this study, we investigated the involvement of NTL in the reproductive behavio...
-
Article
A new tau dephosphorylation-targeting chimera for the treatment of tauopathies
Abnormal accumulation of hyperphosphorylated tau protein plays a pivotal role in a collection of neurodegenerative diseases named tauopathies, including Alzheimer’s disease (AD). We have recently conceptualize...
-
Article
The Preparation of Magnesium from Magnesia by Using Atmospheric Microwave Al-C Reduction Method
Microwave irradiation has exceptional advantages for materials preparation and extractive metallurgy with its unique and distinguished characteristic of volumetric and selective heating. Here, we design a new ...
-
Article
A developed Criminisi algorithm based on particle swarm optimization (PSO-CA) for image inpainting
As a robust digital image inpainting technology, the Criminisi algorithm (CA) has been widely used. However, its high running time that it needs to search in the entire undamaged area of the image to determine...
-
Article
Machine Learning: A Potential Therapeutic Tool to Facilitate Neonatal Therapeutic Decision Making
Bacterial infection is one of the major causes of neonatal morbidity and mortality worldwide. Finding rapid and reliable methods for early recognition and diagnosis of bacterial infections and early individual...
-
Article
Electrochemical sensor based on triazinyl covalent organic framework for detection of dopamine
The covalent organic framework (COF-1) containing triazine group was prepared by solvothermal method, and its structure and morphology were characterized by XRD, BET, FIRT, SEM, TEM, etc. COF-1 was used for th...
-
Article
Genetic and prognostic analysis of blastoid and pleomorphic mantle cell lymphoma: a multicenter analysis in China
Blastoid or pleomorphic mantle cell lymphoma (B/P-MCL) is characterized by high invasiveness and unfavorable outcomes, which is still a challenge for treating MCL. This retrospective study was performed to com...
-
Article
Hematological and Neurological Expressed 1 Promotes Tumor Progression Through mTOR Signaling in Ovarian Cancer
Ovarian cancer (OV) is a highly aggressive malignancy with poor prognosis due to recurrence and drug resistance. Therefore, it is imperative to investigate the key molecular mechanisms underlying OV progressio...
-
Article
Open AccessAssociation of elevated circulating monocyte-platelet aggregates with hypercoagulability in patients with nephrotic syndrome
Hypercoagulability emerges as a central pathological feature and clinical complication in nephrotic syndrome. Increased platelet activation and aggregability are closely related to hypercoagulability in nephro...
-
Article
Oncoprotein LAMTOR5-mediated CHOP silence via DNA hypermethylation and miR-182/miR-769 in promotion of liver cancer growth
C/EBP homologous protein (CHOP) triggers the death of multiple cancers via endoplasmic reticulum (ER) stress. However, the function and regulatory mechanism of CHOP in liver cancer remain elusive. We have reporte...
-
Article
Safety and effectiveness of tunneled peripherally inserted central catheters versus conventional PICC in adult cancer patients
This study aimed to compare the safety and effectiveness of tunneled peripherally inserted central catheters (T-PICC) vs. conventional PICCs (C-PICC) in adult cancer patients.
-
Article
5G Metaverse in Education
The development of 5G private networks harbors immense potential for technological innovation, significantly enhancing digital connectivity and performance. This advancement has unlocked opportunities for pion...
-
Article
Open AccessNon-invasive brain stimulation for treatment-resistant schizophrenia: protocol of a systematic review and network meta-analysis
Non-invasive brain stimulation (NIBS) is a promising intervention for treatment-resistant schizophrenia. However, there are multiple available techniques and a comprehensive synthesis of evidence is lacking. T...
