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    Article

    Serum and cerebrospinal fluid levels of interleukin-18 in human immunodeficiency virus type 1-associated central nervous system disease

    Interleukin-18 (IL-18) is a proinflammatory cytokine released by macrophages that strongly stimulates the production of interferon-γ, thereby linking innate and acquired immunity. Its role in human immunodefic...

    Hans-Jürgen von Giesen, Sebastian Jander, Hubertus Köller… in Journal of NeuroVirology (2004)

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    Article

    Functional CXCR4 receptor development parallels sensitivity to HIV-1 gp120 in cultured rat astroglial cells but not in cultured rat cortical neurons

    The α chemokine receptor CXCR4 is used as the major coreceptor for the cell entry of T-cell-tropic human immunodeficiency virus-1 (HIV-1) isolates. Activation of this coreceptor by its natural ligand SDF1α, is as...

    Hubertus Köller, Heiner Schaal, Claudia Rosenbaum… in Journal of NeuroVirology (2002)