163 Result(s)
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Huawei **n
Life Sciences
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Article
Open AccessUnveiling biosynthetic potential of an Arctic marine-derived strain Aspergillus sydowii MNP-2
A growing number of studies have demonstrated that the polar regions have the potential to be a significant repository of microbial resources and a potential source of active ingredients. Genome mining strateg...
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The effects of methyl jasmonate on volatile compounds and activity of aroma-related enzymes in tobacco
Flue-cured tobacco, a member of the Solanaceae family, is widely utilized as a model organism in both fundamental and applied scientific research. This study set out to evaluate the influence of the exogenous age...
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Article
Delivery of neurotrophin-3 by RVG-Lamp2b-modified mesenchymal stem cell-derived exosomes alleviates facial nerve injury
We aim to investigate the effect of RVG-Lamp2b-modified exosomes (exos) loaded with neurotrophin-3 (NT-3) on facial nerve injury. Exos were collected from control cells (Ctrl Exo) or bone marrow mesenchymal st...
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Identification and Expression Profiles of Auxin-Related Gene Families Involved in Fiber Development in Jute (Corchorus capsularis)
The ARF (Auxin response factor), GH3 (Gretchen Hagen 3), and Aux/IAA (Auxin/indole-3-acetic acid) gene families are key components in auxin signaling pathway and function as regulators of growth in plants. Howeve...
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Impact of knockout of dual-specificity protein phosphatase 5 on structural and mechanical properties of rat middle cerebral arteries: implications for vascular aging
Vascular aging influences hemodynamics, elevating risks for vascular diseases and dementia. We recently demonstrated that knockout (KO) of Dusp5 enhances cerebral and renal hemodynamics and cognitive function. Th...
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Aridity-driven divergence in soil microbial necromass carbon in alpine grasslands of the Tibetan Plateau
Soil microbial necromass carbon (MNC) contributes to the long-term stability of soil organic carbon (SOC). However, the response of MNC across aridity gradients remains unclear, especially in vulnerable alpine...
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Open AccessMetabolomics and proteomics insights into subacute ruminal acidosis etiology and inhibition of proliferation of yak rumen epithelial cells in vitro
Untargeted metabolomics and proteomics were employed to investigate the intracellular response of yak rumen epithelial cells (YRECs) to conditions mimicking subacute rumen acidosis (SARA) etiology, including e...
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Open AccessCorrection: Transcriptomics and metabolomics of blood, urine and ovarian follicular fuid of yak at induced estrus stage
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Transcriptional regulators of secondary metabolite biosynthesis in Streptomyces
In the post-genome era, great progress has been made in metabolic engineering using recombinant DNA technology to enhance the production of high-value products by Streptomyces. With the development of microbial g...
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Open AccessOptimization of fermentation conditions and medium components for chrysomycin a production by Streptomyces sp. 891-B6
Chrysomycin A (CA) is a promising antibiotic for treatment of Gram-positive bacterial infections and cancers. In order to enhance CA yield, optimization of fermentation conditions and medium components was car...
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Exploratory biological coordinate analysis on 2,4-epi-brassinolide-induced the size change of leaf angle in tobacco seedlings
Leaf angle (LA) is a key plant architectural trait contributing to crop yield. The chemical 2,4-epibrassinolide (EBR) is a bioactive form of brassinosteroids (BRs) and plays a significant role in influencing p...
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Potential spatial distributions of Tibetan antelope and protected areas on the Qinghai-Tibetan Plateau, China
Climate change has been regarded as a major factor affecting the geographic distribution of many endemic rare species on the Qinghai-Tibetan Plateau. Tibetan antelope, an endemic rare wildlife, is identified a...
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Article
STK32C modulates doxorubicin resistance in triple-negative breast cancer cells via glycolysis regulation
Understanding the mechanisms underlying doxorubicin resistance in triple-negative breast cancer (TNBC) holds paramount clinical significance. In our study, we investigate the potential of STK32C, a little-expl...
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Acid tolerance response of Salmonella during the squid storage and its amine production capacity analysis
Salmonella exhibits a strong inducible acid tolerance response (ATR) under weak acid conditions, and can also induce high-risk strains that are highly toxic, acid resistant, and osmotic pressure resistant to a...
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Open AccessTranscriptomics and metabolomics of blood, urine and ovarian follicular fluid of yak at induced estrus stage
To gain a deeper understanding of the metabolic differences within and outside the body, as well as changes in transcription levels following estrus in yaks, we conducted transcriptome and metabolome analyses ...
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Article
Open AccessResponse of rhizosphere soil physicochemical properties and microbial community structure to continuous cultivation of tobacco
The health of rhizosphere soil microorganisms is an important indicator to evaluate soil quality. Therefore, understanding the response of rhizosphere soil microorganisms to tobacco crop succession is crucial ...
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Author Correction: Redesigning the tomato fruit shape for mechanized production
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Characterization of a novel sucrose phosphorylase from Paenibacillus elgii and its use in biosynthesis of α-arbutin
α-Arbutin, a naturally occurring glycosylated derivative of hydroquinone (HQ), effectively inhibits melanin biosynthesis in epidermal cells. It is widely recognized as a fourth-generation whitening agent withi...
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Effects of dietary supplementation of gallic tanninc acid on growth, intestinal digestive enzymes activity, innate immunity, morphology, and microbial composition of Cyprinus carpio
In this study, we investigated the effects of gallic tannic acid (GTA) supplementation on the growth performance, intestinal digestive enzymes, morphology and microbial composition of common carp (Cyprinus carpio
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Open AccessElectroacupuncture promotes neurogenesis in the dentate gyrus and improves pattern separation in an early Alzheimer's disease mouse model
Impaired pattern separation occurs in the early stage of Alzheimer’s disease (AD), and hippocampal dentate gyrus (DG) neurogenesis participates in pattern separation. Here, we investigated whether spatial memo...
