-
Article
Open AccessHeterogeneous gene expression during early arteriovenous fistula remodeling suggests that downregulation of metabolism predicts adaptive venous remodeling
Clinical outcomes of arteriovenous fistulae (AVF) for hemodialysis remain inadequate since biological mechanisms of AVF maturation and failure are still poorly understood. Aortocaval fistula creation (AVF grou...
-
Article
Open AccessThe application of tissue-engineered fish swim bladder vascular graft
Small diameter (< 6 mm) prosthetic vascular grafts continue to show very low long-term patency, but bioengineered vascular grafts show promising results in preclinical experiments. To assess a new scaffold sou...
-
Article
Open AccessEph-B4 regulates adaptive venous remodeling to improve arteriovenous fistula patency
Low rates of arteriovenous fistula (AVF) maturation prevent optimal fistula use for hemodialysis; however, the mechanism of venous remodeling in the fistula environment is not well understood. We hypothesized ...
-
Article
Open AccessCovalent modification of pericardial patches for sustained rapamycin delivery inhibits venous neointimal hyperplasia
Prosthetic grafts and patches are commonly used in cardiovascular surgery, however neointimal hyperplasia remains a significant concern, especially under low flow conditions. We hypothesized that delivery of r...
