2,992 Result(s)

Article

Cardiotoxic protein from edible mushrooms

THE cardiotoxic protein volvatoxin has been isolated from the edible mushroom, Volvariella volvaceae¹. We have now isolated another cardiotoxic protein from the edible mushroom Flammulina velutipes (Curt. ex Frie...

JUNG-YAW LIN, YIE-JANE LIN, CHENG-CHUNG CHEN, HUA-LIN WU, GUEY-YUEH SHI… in Nature (1974)

Chapter

Numerical Weather Prediction Relevant to the Monsoon Problem

In this short paper we have identified some of the modelling groups that have the capability of simulating or carrying out short range numerical weather prediction over the monsoon belt. We have next outlined ...

T. N. Krishnamurti, John Molinari, Hua-Lu Pan, Vince Wong in Monsoon Dynamics (1978)

Chapter

A Mathematics Analysis for the Experimental Study of Plate Springback at the Top Roll Contact in Four-roll Plate Bending

The bending mechanics of the continuous four-roll bending of plate is mainly an elastic-elastoplastic problem, thus an experimental study of the production process requires an estimation of the amount of plate...

M. Hua, K. Baines, I. M. Cole in Advances in Manufacturing Technology II (1987)

Article

Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone

Untransformed T-cell clones maintained in culture are dependent on signals transmitted through their antigen receptors (Ti; α and β chains associated with the CD3 molecules) for growth and effector function^1,2. F...

Anne-Marie Schmitt-Verhulst, Annick Guimezanes, Claude Boyer, Martin Poenie… in Nature (1987)

Chapter

Metallgießen

Dies sind oft zitierte Zeilen aus der Yong Ye Fu (Ode auf das Gießen), geschrieben von dem Dichter Cao Pi aus der **-Dynastie (265–420), welche die schwungvolle Szenerie des Metallgießens im alten China gut besc...

Hua Jueming in Wissenschaft und Technik im alten China (1989)

Article

Receptor binding redefined by a structural switch in a mutant human insulin

CRYSTAL structures of insulin have been determined in various distinct forms^1–5, the relevance of which to receptor recognition has long been the subject of speculation^2,6,7. Recently the crystal structure of an ...

Qing **n Hua, Steven E. Shoelson, Michel Kochoyan, Michael A. Weiss in Nature (1991)

Chapter

Mechanism of Protein Kinase C-Mediated Signal Transduction

Protein kinase C (PKC) plays a pivotal role in the regulation of numerous cellular functions in response to a variety of external stimuli that cause the increase in [Ca²⁺], sn-1,2-diacylglycerol (DAG), and cis-un...

Kuo-** Huang, Freesia L. Huang… in Adenine Nucleotides in Cellular Energy Tra… (1992)

Article

Wild-type p53 activates transcription in vitro

THE p53 protein is an important determinant in human cancer and regulates the growth of cells in culture^1–3. It is known to be a sequence-specific DNA-binding protein^4,5 with a powerful activation domain^6–8, but ...

George Farmer, Jill Bargonetti, Hua Zhu, Paula Friedman, Ron Prywes, Carol Prives in Nature (1992)

Article

Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II

Phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II is believed to control the transition from transcription initiation to elongation. The general transcription factor II...

Hua Lu, Leigh Zawel, Laurent Fisher, Jean-Marc Egly, Danny Reinberg in Nature (1992)

Article

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

ALZHEIMER'S disease (AD) is the most common cause of progressive intellectual failure in aged humans. AD brains contain numerous amyloid plaques surrounded by dystrophic neurites, and show profound synaptic lo...

Dora Games, David Adams, Ree Alessandrini, Robin Barbour, Patricia Borthelette… in Nature (1995)

Article

Crystal structure of a TFIIB–TBP–TATA-element ternary complex

The crystal structure of the transcription factorIIB (TFIIB)/TATA box-binding protein (TBP)/ TATA-element ternary complex is described at 2.7 Å resolution. Core TFIIB resembles cyclin A, and recognizes the pre...

Dimitar B. Nikolov, Hua Chen, Elaine D. Halay, Anny A. Usheva, Koji Hisatake… in Nature (1995)

Article

Requirement for neuregulin receptor erbB2 in neural and cardiac development

THE receptor erbB2/neu is a member of the epidermal growth factor receptor (EGFR or erbB) family that also includes erbB3 and erbB4¹. Amplification of the erbB2/neu gene is found in many cancer types and its over...

Kuo-Fen Lee, Horst Simon, Hua Chen, Brian Bates, Mien-Chie Hung… in Nature (1995)

Article

Requirement of mammalian DNA polymerase-β in base-excision repair

SYNTHESIS of DNA by DNA polymerase-β is distributive on single-stranded DNA templates, but short DNA gaps with a 5′ PO₄ in the gap are filled processively to completion^1,2. In vitro studies have suggested a role ...

Robert W. Sobol, Julie K. Horton, Ralf Kühn, Hua Gu, Rakesh K. Singhal… in Nature (1996)

Article

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis

THE induction of programmed cell death, or apoptosis, involves activation of a signalling system, many elements of which remain unknown¹. The sphingomyelin pathway, initiated by hydrolysis of the phospholipid sph...

Marcel Verheij, Ron Bose, **n Hua Lin, Bei Yao, W. David Jarvis, Steven Grant… in Nature (1996)

Article

Discovery and significance of microfossils from Qinbaikouian Dazhuang Formation in Luonan, Shaanxi Province

Zhe Chen, Hong Hua, Wanchou Jian, Yunxu Hu in Chinese Science Bulletin (1997)

Article

Screening and structure analysis of a cDNA encoding RNA-binding protein

Kuiyi **ng, Hua **n, Kaiming Cao, Chongrong Sun in Chinese Science Bulletin (1997)

Article

Presenilin 1 is required for Notch 1 and Dll1 expression in the paraxial mesoderm

Approximately 10% of cases of Alzheimer's disease are familial and associated with autosomal dominant inheritance of mutations in genes encoding the amyloid precursor protein¹, presenilin 1 (PS1)² and presenilin ...

Philip C. Wong, Hui Zheng, Hua Chen, Mark W. Becher, Dalip J. S. Sirinathsinghji… in Nature (1997)