396 Result(s)

Article

Early change of plasma Epstein-Barr virus DNA load and the viral lytic genome level could positively predict clinical outcome in recurrent or metastatic nasopharyngeal carcinoma receiving anti-programmed cell death 1 monotherapy

Patients with recurrent or metastatic nasopharyngeal carcinoma (RM-NPC) have proven benefit from anti-programmed cell death 1 (anti-PD-1) monotherapy. Here, we retrospectively analyze the association of plasma...

Shaoyan Lin, Huaqiang Zhou, Gang Chen, **hui Xue, Qianwen Liu, Jianing Li… in BMC Cancer (2024)

Article

LMO family gene polymorphisms and Wilms tumor susceptibility in Chinese children: a five-center case-control study

Wilms tumor is the most prevalent embryonal kidney malignancy in children worldwide. Previous genome-wide association study (GWAS) identified that LIM domain only 1 (LMO1) gene polymorphisms affected the suscepti...

Wen Fu, Linqing Deng, **aosong Yan, Rui-** Hua, Jiao Zhang, Haixia Zhou… in BMC Cancer (2024)

Article

Prognostic significance of platelet‑to‑albumin ratio in patients with nasopharyngeal carcinoma receiving concurrent chemoradiotherapy: a retrospective study of 858 cases

Despite evidence supporting the high correlation of the novel platelet-to-albumin ratio (PAR) with survival in diverse malignancies, its prognostic relevance in nasopharyngeal carcinoma (NPC) remains underexpl...

**n Hua, Fei Xu, Wei Shi, Zhi-Qing Long, **n Huang, Fang-Fang Duan… in BMC Cancer (2024)

Article

A novel surgical scheme for hepatectomy in hepatocellular carcinoma patients with clinically significant portal hypertension

Clinically significant portal hypertension (CSPH) seriously affects the feasibility and safety of surgical treatment for hepatocellular carcinoma (HCC) patients. The aim of this study was to establish a new su...

Jia-zhou Ye, Hua-ze Lu, Can Zeng, Guo Lei, **ao-bo Wang, Jie Chen, Tao Bai… in BMC Cancer (2024)

Article

Correlation between hemoglobin and the risk of common malignant tumors: a 1999–2020 retrospective analysis and causal association analysis

The role of hemoglobin (HGB) in common malignant tumors remains unclear.

Guo-Sheng Li, Tao Huang, **g-**ao Li, Jun Liu, **ang Gao, Nuo Yang… in BMC Cancer (2024)

Article

Safety and efficacy of multi-target TKI combined with nivolumab in check-point inhibitor-refractory patients with advanced NSCLC: a prospective, single-arm, two-stage study

Resistance to immune checkpoint inhibitors (ICIs) represents a major unmet medical need in non-small cell lung cancer (NSCLC) patients. Vascular endothelial growth factor (VEGF) inhibition may reverse a suppre...

Bo Zhang, Hongyu Liu, Chunlei Shi, Zhiqiang Gao, Runbo Zhong, Aiqin Gu… in BMC Cancer (2024)

Article

Integrated multi-omics analyses revealed the association between rheumatoid arthritis and colorectal cancer: MYO9A as a shared gene signature and an immune-related therapeutic target

Our study aims to explore the relationship, shared gene signature, and the underlying mechanisms that connect rheumatoid arthritis (RA) to colorectal cancer (CRC).

Zhi-Qing Zhan, Ze-Min Huang, Qi-Wen Lan, Yu-Hua Luo, Jia-**n Li… in BMC Cancer (2024)

Article

GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity

DNA double-strand break (DSB) induction and repair are important events for determining cell survival and the outcome of cancer radiotherapy. The DNA-dependent protein kinase (DNA-PK) complex functions at the ...

Yang Han, Hongling Zhao, Gang Li, ** Jia, Hejiang Guo… in British Journal of Cancer (2024)

Article

CA-125 elimination rate constant K (KELIM) as a promising predictor of complete cytoreduction after neoadjuvant chemotherapy in advanced ovarian cancer patients: a retrospective study from two Chinese hospitals

The modeled CA-125 elimination constant K (KELIM) is a potential marker of tumor chemosensitivity in ovarian cancer patients treated with neoadjuvant chemotherapy (NACT) before interval surgery. The objective ...

Cheng Li, Qiulin Cui, Xuanhui Wang, Shuzhong Yao, Hua Tu, Ming Chen in BMC Cancer (2024)

Article

Prediction of esophageal cancer risk based on genetic variants and environmental risk factors in Chinese population

Results regarding whether it is essential to incorporate genetic variants into risk prediction models for esophageal cancer (EC) are inconsistent due to the different genetic backgrounds of the populations stu...

Haiyan Liu, Keming Li, Junfen **a, Jicun Zhu, Yifan Cheng, **aoyue Zhang… in BMC Cancer (2024)

Article

Dynamic genomic changes in methotrexate-resistant human cancer cell lines beyond DHFR amplification suggest potential new targets for preventing drug resistance

Although DHFR gene amplification has long been known as a major mechanism for methotrexate (MTX) resistance in cancer, the early changes and detailed development of the resistance are not yet fully understood.

**ang-Ning Meng, **-Fa Ma, Yang-He Liu, Si-Qing Li, Xu Wang… in British Journal of Cancer (2024)

Article

Association of the TRIM family protein with survival outcomes and clinicopathological features in colorectal cancer: a systematic review and meta-analysis

The tripartite motif (TRIM) proteins have been reported to play crucial roles in various malignancies. However, the clinical significance of TRIM proteins in colorectal cancer (CRC) remains controversial. This...

Ying Wu, Chen Chen, **an Hua, Chunhua Zhao, Han Min in BMC Cancer (2024)

Article

Investigation of correlation between shear wave elastography and lymphangiogenesis in invasive breast cancer and diagnosis of axillary lymph node metastasis

Accurate evaluation of axillary lymph node metastasis (LNM) in breast cancer is very important. A large number of hyperplastic and dilated lymphangiogenesis cases can usually be found in the pericancerous tiss...

Bo Li, Shaochun Dai, Qiucheng Wang, Hui **g, Hua Shao, Lei Zhang, Ling Qin… in BMC Cancer (2024)

Article

Nomogram to predict overall survival of patients receiving radical gastrectomy and incomplete peri-operative adjuvant chemotherapy for stage II/III gastric cancer: a retrospective bi-center cohort study

To establish a nomogram to predict the probability of survival of patients with stage II/III gastric cancer (GC) who received incomplete peri-operative adjuvant chemotherapy (PAC).

Dian Liu, Hu Quan, Min Ma, Huijun Zhou, **aolin Yang, Zhengchun Wu, Jia Luo… in BMC Cancer (2024)

Article

Retraction Note: Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191

Deyu Huang, Chunhua Bi, Qingxi Zhao, Xueli Ding, Cheng Bian, Hui Wang… in BMC Cancer (2024)