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Relationship of imipenem therapeutic drug monitoring to clinical outcomes in critically ill patients: a retrospective cohort study

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  1. Article

    Correction to: K do** stabilizes three-dimensional K0.2Na1.3Mn0.5O2-δ as high-performance cathode for sodium-ion batteries

    Jia-Hao Xu, You-Huan Zhu, Wei-Min Yang, Hua Cheng, Zhou-Guang Lu in Rare Metals (2024)

  2. Article

    Open Access

    A(H2N2) and A(H3N2) influenza pandemics elicited durable cross-reactive and protective antibodies against avian N2 neuraminidases

    Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the 1957 pan...

    Zaolan Liang, **a Lin, Lihong Sun, Kimberly M. Edwards in Nature Communications (2024)

  3. Article

    Open Access

    Relationships between apolipoprotein E and insulin resistance in patients with obstructive sleep apnoea: a large-scale cross-sectional study

    Obstructive sleep apnoea (OSA) is commonly associated with insulin resistance (IR) and dyslipidaemia. Apolipoprotein E (APOE) plays important roles in lipid metabolism. The study aimed to disentangle the multi...

    ZhiCheng Wei, Ling Tian, Huajun Xu, Chenyang Li, Kejia Wu in Nutrition & Metabolism (2024)

  4. Article

    Correction: Relationship of imipenem therapeutic drug monitoring to clinical outcomes in critically ill patients: a retrospective cohort study

    Ye**g Wu, Zhangyang Lu, Pei Liang in Naunyn-Schmiedeberg's Archives of Pharmaco… (2024)

  5. Article

    Open Access

    Impact analysis of digital trade on carbon emissions from the perspectives of supply and demand

    Amidst the escalating challenge of global climate change, it is imperative to further explore whether digital trade, as an emerging element in the global development landscape, can reduce carbon emissions and ...

    Huayou Zhu, Wei** Bao, Manman Qin in Scientific Reports (2024)

  6. Article

    Open Access

    The changes in ocular torsion after unilateral lateral rectus recession-medial rectus resection for intermittent exotropia

    We aim to explore the alterations of objective ocular torsion after unilateral lateral rectus recession-medial rectus resection (R&R) for intermittent exotropia (IXT). Seventy-two IXT patients undergoing R&R b...

    Changyang Liu, Jiasu Liu, Huailin Zhu, Lan Zhang, Mingjun Gao in Scientific Reports (2024)

  7. Article

    Open Access

    Identification and characterization of Varicella Zoster Virus circular RNA in lytic infection

    This study investigates the role of circular RNAs (circRNAs) in the context of Varicella-Zoster Virus (VZV) lytic infection. We employ two sequencing technologies, short-read sequencing and long-read sequencin...

    Shaomin Yang, Di Cao, Dabbu Kumar Jaijyan, Mei Wang, Jian Liu in Nature Communications (2024)

  8. Article

    Open Access

    SPAG5 deficiency activates autophagy to reduce atherosclerotic plaque formation in ApoE−/− mice

    Autophagy, as a regulator of cell survival, plays an important role in atherosclerosis (AS). Sperm associated antigen 5 (SPAG5) is closely associated with the classical autophagy pathway, PI3K/Akt/mTOR signali...

    Liangyun Guo, Hui**g Yuan, Huayao Zhu, Jie Zhou, Zixin Wan in BMC Cardiovascular Disorders (2024)

  9. Article

    Open Access

    Uncovering the essence of diverse media biases from the semantic embedding space

    Media bias widely exists in the articles published by news media, influencing their readers’ perceptions, and bringing prejudice or injustice to society. However, current analysis methods usually rely on human...

    Hong Huang, Hua Zhu, Wenshi Liu, Hua Gao in Humanities and Social Sciences Communicati… (2024)

  10. Article

    Open Access

    Independent relationship between sleep apnea-specific hypoxic burden and glucolipid metabolism disorder: a cross-sectional study

    Obstructive sleep apnea (OSA) is associated with abnormal glucose and lipid metabolism. However, whether there is an independent association between Sleep Apnea-Specific Hypoxic Burden (SASHB) and glycolipid m...

    Chenyang Li, Yu Peng, **aoyue Zhu, Yupu Liu, Jianyin Zou in Respiratory Research (2024)

  11. Article

    Open Access

    EGF-like growth factors upregulate pentraxin 3 expression in human granulosa-lutein cells

    The epidermal growth factor (EGF)-like factors, comprising amphiregulin (AREG), betacellulin (BTC), and epiregulin (EREG), play a critical role in regulating the ovulatory process. Pentraxin 3 (PTX3), an essen...

    Yuxi Li, Hsun-Ming Chang, Hua Zhu, Ying-Pu Sun in Journal of Ovarian Research (2024)

  12. Article

    Open Access

    Risk factors and management of gastrointestinal bleeding in patients with or without antiplatelet and anticoagulation therapy: a multicenter real-world prospective study

    Antiplatelet and anticoagulation drugs complicate acute gastrointestinal bleeding (GIB) patients. Limited data about the risk factors and patient management has been presented. This study explored the associat...

    Wenlin Hao, Anlei Liu, Huadong Zhu, Xuezhong Yu, Gang Chen, Jun Xu in BMC Gastroenterology (2024)

  13. Article

    Open Access

    Venetoclax plus dose-adjusted R-EPOCH (VR-DA-EPOCH) or G-EPOCH bridging to subsequent cellular therapy for the patients with transformed lymphoma a single center clinical experience

    Indolent lymphoma, including chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and follicular lymphoma (FL), can undergo histological transformation into an aggressive subtype, typically diffus...

    Shuchao Qin, Rui Jiang, Luomengjia Dai, Yi Miao, Yeqin Sha in Annals of Hematology (2024)

  14. Article

    Open Access

    Early Onset Intrahepatic Cholangiocarcinoma: Clinical Characteristics, Oncological Outcomes, and Genomic/Transcriptomic Features

    Data on clinical characteristics and disease-specific prognosis among patients with early onset intrahepatic cholangiocarcinoma (ICC) are currently limited.

    Diamantis I. Tsilimigras MD, Xu Han MD, PhD in Annals of Surgical Oncology (2024)

  15. Article

    Open Access

    Risk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China

    Pediatric antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a life-threatening systemic vasculitis featured by liability to renal involvement. However, there are few studies on the risk factor...

    Li-Wen Tan, Jun-Li Wan, Chun-Hua Zhu, Hong Xu, Zheng-Kun **a in World Journal of Pediatrics (2024)

  16. Article

    Open Access

    Nomogram predictive model for in-hospital mortality risk in elderly ICU patients with urosepsis

    Urinary tract infection (UTI) is a common cause of sepsis. Elderly patients with urosepsis in intensive care unit (ICU) have more severe conditions and higher mortality rates owing to factors such as advanced ...

    Jian Wei, Ruiyuan Liang, Siying Liu, Wanguo Dong, Jian Gao in BMC Infectious Diseases (2024)

  17. Article

    Open Access

    The clinical value of mNGS of bronchoalveolar lavage fluid versus traditional microbiological tests for pathogen identification and prognosis of severe pneumonia (NT-BALF):study protocol for a prospective multi-center randomized clinical trial

    Early, rapid, and accurate pathogen diagnosis can help clinicians select targeted treatment options, thus improving prognosis and reducing mortality rates of severe pneumonia. Metagenomic next-generation seque...

    **ao Song, Hui Jiang, Liang Zong, Di Shi, Huadong Zhu in Trials (2024)

  18. Article

    Open Access

    Exploring natural killer cell-related biomarkers in multiple myeloma: a novel nature killer cell-related model predicting prognosis and immunotherapy response using single-cell study

    Natural killer cells (NKs) may be involved in multiple myeloma (MM) progression. The present study elucidated the correlation between NKs and the progression of MM using single-cell binding transcriptome probe...

    **g Zhao, **aoning Wang, Huachao Zhu, Suhua Wei in Clinical and Experimental Medicine (2024)

  19. Article

    Open Access

    Circulating tumor cell-derived exosome–transmitted long non-coding RNA TTN-AS1 can promote the proliferation and migration of cholangiocarcinoma cells

    Exosomes assume a pivotal role as essential mediators of intercellular communication within tumor microenvironments. Within this context, long noncoding RNAs (LncRNAs) have been observed to be preferentially s...

    Xu Zhou, **aohan Kong, Jun Lu, Heng Wang, Meng Liu in Journal of Nanobiotechnology (2024)

  20. Article

    Open Access

    Diversity Patterns of Eukaryotic Phytoplankton in the Medog Section of the Yarlung Zangbo River

    As one of the important biodiversity conservation areas in China, the ecosystem in the lower reaches of the Yarlung Zangbo River is fragile, and is particularly sensitive to global changes. To reveal the diver...

    Huan Zhu, Shuyin Li, Zhihua Wu, **ong **ong, Pengcheng Lin, Benwen Liu in Microbial Ecology (2024)

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