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  1. Article

    Open Access

    Long-term complications and outcomes of augmentation cystoplasty in children with neurogenic bladder

    Augmentation cystoplasty (AC) is an effective surgical procedure for patients with neurogenic bladder whenever conservative treatments have failed. The present study aimed to determine the risks of metabolic c...

    Jei-Wen Chang, Fang-Cheng Kuo, Tzu-Ching Lin, Tai-Wai Chin in Scientific Reports (2024)

  2. Article

    Open Access

    Proton pump inhibitors reduce the survival of advanced lung cancer patients with therapy of gefitinib or erlotinib

    Gefitinib and erlotinib are the first-line tyrosine kinase inhibitors (TKI) for advanced non-small-cell lung cancer. However, co-administration of either drug with proton pump inhibitors (PPI) or histamine-2 r...

    Chia-Han Lee, Mei-Chiou Shen, Ming-Ju Tsai, Jung-San Chang in Scientific Reports (2022)

  3. Article

    Open Access

    Survival outcomes of management in metastatic gastric adenocarcinoma patients

    Chemotherapy is generally considered as the main treatment for metastatic gastric adenocarcinoma. The role of gastrectomy for metastatic gastric cancer without obvious symptoms is controversial. The objective ...

    Huang-Ming Hu, Hui-Jen Tsai, Hsiu-Ying Ku, Su-Shun Lo, Yan-Shen Shan in Scientific Reports (2021)

  4. Article

    Open Access

    Oxytocin maintains lung histological and functional integrity to confer protection in heat stroke

    Oxytocin (OT) has been reported to have a protective effect in lipopolysaccharide-induced experimental acute lung injury (ALI). However, its role in heat stroke-related ALI has never been investigated. Herein,...

    Cheng-Hsien Lin, Cheng-Chia Tsai, Tzu-Hao Chen, Ching-** Chang in Scientific Reports (2019)

  5. Article

    Open Access

    Promoting Induced Pluripotent Stem Cell-driven Biomineralization and Periodontal Regeneration in Rats with Maxillary-Molar Defects using Injectable BMP-6 Hydrogel

    Periodontal disease may cause considerable destruction of alveolar bone, periodontal ligaments (PDLs) and cementum and even lead to progressive oral dysfunction. Periodontal tissue regeneration is the ultimate...

    Ke-Hung Chien, Yuh-Lih Chang, Mong-Lien Wang, Jen-Hua Chuang in Scientific Reports (2018)

  6. Article

    Open Access

    In search of tail-anchored protein machinery in plants: reevaluating the role of arsenite transporters

    Although the mechanisms underlying selective targeting of tail-anchored (TA) membrane proteins are well established in mammalian and yeast cells, little is known about their role in mediating intracellular mem...

    Manuel Maestre-Reyna, Shu-Mei Wu, Yu-Ching Chang, Chi-Chih Chen in Scientific Reports (2017)

  7. Article

    Open Access

    Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan

    Kawasaki disease (KD) is an acute, inflammatory and self-limited vasculitis affecting infants and young children. Coronary artery aneurysm (CAA) formation is the major complication of KD and the leading cause ...

    Ying-Ju Lin, Jeng-Sheng Chang, **ang Liu, Hsinyi Tsang in Scientific Reports (2015)

  8. Article

    Open Access

    Longitudinal risk of herpes zoster in patients with non-Hodgkin lymphoma receiving chemotherapy: A nationwide population-based study

    This study investigated the incidence of and risk factors for herpes zoster in patients with non-Hodgkin lymphoma (NHL) who were receiving anti-lymphoma treatment. The overall incidence density of herpes zoste...

    Shih-Feng Cho, Wan-Hsuan Wu, Yi-Hsin Yang, Yi-Chang Liu in Scientific Reports (2015)