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    Tacrolimus-loaded chitosan-coated nanostructured lipid carriers: preparation, optimization and physicochemical characterization

    Tacrolimus as an immunosuppressive drug shows poor solubility in aqueous media, accompanied by a low/variable bioavailability in peroral administration due to its high first-pass metabolism. Therefore, in this...

    Somayeh Dasineh, Maryam Akbarian, Hossein Ali Ebrahimi, Gity Behbudi in Applied Nanoscience (2021)