6 Result(s)
within
Hong-Wei Shao
English
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Article
Efficient Editing of an Adenoviral Vector Genome with CRISPR/Cas9
Immunotherapy based on genetic modification of T cells has played an important role in the treatment of tumors and viral infections. Moreover, adenoviral vectors engineered with improved safety due to their in...
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Article
Open AccessPercutaneous transforaminal endoscopic surgery (PTES) for symptomatic lumbar disc herniation: a surgical technique, outcome, and complications in 209 consecutive cases
We designed an easy posterolateral transforaminal endoscopic decompression technique, termed PTES, for radiculopathy secondary to lumbar disc herniation. The purpose of the study is to describe the technique o...
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Article
Open AccessInfluence of cell physiological state on gene delivery to T lymphocytes by chimeric adenovirus Ad5F35
Adoptive transfer of genetically-modified T cells is a promising approach for treatment of both human malignancies and viral infections. Due to its ability to efficiently infect lymphocytes, the chimeric adeno...
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Article
Skin temperature oscillation model for assessing vasomotion of microcirculation
It has been proved that there exists a certain correlation between fingertip temperature oscillations and blood flow oscillations. In this work, a porous media model of human hand is presented to investigate h...
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Article
Forced expression of indoleamine-2,3-dioxygenase in human umbilical cord-derived mesenchymal stem cells abolishes their anti-apoptotic effect on leukemia cell lines in vitro
The ability of mesenchymal stem cells (MSCs) to preserve cancer cells potentially constitutes the adverse effect of MSC-based cell therapy in the context of hematologic malignancy. In an effort to reverse this...
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Article
Identification of a novel HLA-A2-restricted mutated Survivin epitope and induction of specific anti-HCC CTLs that could effectively cross-recognize wild-type Survivin antigen
Peptide vaccine based on tumor-associated antigen (TAA), which usually belongs to self-antigen with poor immunogenicity, has been considered as an attractive option for treatment of malignant tumors. The ideal...
