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  1. Article

    Open Access

    Enhancing efficiency of protein language models with minimal wet-lab data through few-shot learning

    Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Pre-trained protein language models have achieved state-of-the-art performance in predicting protein fitness w...

    Ziyi Zhou, Liang Zhang, Yuanxi Yu, Banghao Wu, Mingchen Li in Nature Communications (2024)

  2. Article

    Open Access

    Cloud inversion analysis of surrounding rock parameters for underground powerhouse based on PSO-BP optimized neural network and web technology

    Aiming at the shortcomings of the BP neural network in practical applications, such as easy to fall into local extremum and slow convergence speed, we optimized the initial weights and thresholds of the BP neu...

    Long Qu, Hong-Qiang **e, Jian-Liang Pei, You-Gen Li, Jia-Ming Wu in Scientific Reports (2024)

  3. Article

    Open Access

    Analytical and experimental analysis of concrete temperature and energy considering open-air environmental variations

    Longwave radiation is an important open-air environmental factor that can significantly affect the temperature of concrete, but it has often been ignored in the temperature analysis of open-air concrete struct...

    Wen-Jian Yang, Peng Li, Li Zhuo, Ming-Liang Pang, Hong-Qiang **e in Scientific Reports (2024)

  4. Article

    Open Access

    Multi-cohort analysis reveals immune subtypes and predictive biomarkers in tuberculosis

    Tuberculosis (TB) remains a significant global health threat, necessitating effective strategies for diagnosis, prognosis, and treatment. This study employs a multi-cohort analysis approach to unravel the immu...

    Ling Li, Tao Wang, Zhi Chen, Jianqin Liang, Hong Ding in Scientific Reports (2024)

  5. Article

    Open Access

    Machine learning-guided realization of full-color high-quantum-yield carbon quantum dots

    Carbon quantum dots (CQDs) have versatile applications in luminescence, whereas identifying optimal synthesis conditions has been challenging due to numerous synthesis parameters and multiple desired outcomes,...

    Huazhang Guo, Yuhao Lu, Zhendong Lei, Hong Bao, Mingwan Zhang in Nature Communications (2024)

  6. Article

    Open Access

    Cu(II)-based complex loaded with drug paclitaxel hydrogels against thyroid cancer and optimizing novel derivatives

    This study introduces a novel approach for synthesizing a Cu(II)-based coordination polymer (CP), {[Cu(L)(4,4´-OBA)]·H2O}n (1), using a mixed ligand method. The CP was successfully prepared by reacting Cu(NO3)2·3...

    Hui-Hui Wang, He-Liang Yin, Wei-Wei Yin, Yong-Li Song, Hong Chen in Scientific Reports (2024)

  7. No Access

    Article

    Imaging surface structure and premelting of ice Ih with atomic resolution

    Ice surfaces are closely relevant to many physical and chemical properties, such as melting, freezing, friction, gas uptake and atmospheric reaction18. Despite extensive experimental and theoretical investigatio...

    Jiani Hong, Ye Tian, Tiancheng Liang, **nmeng Liu, Yizhi Song, Dong Guan in Nature (2024)

  8. Article

    Open Access

    Capture of single Ag atoms through high-temperature-induced crystal plane reconstruction

    The “terminal hydroxyl group anchoring mechanism” has been studied on metal oxides (Al2O3, CeO2) as well as a variety of noble and transition metals (Ag, Pt, Pd, Cu, Ni, Fe, Mn, and Co) in a number of generalized...

    Jiaxin Li, Kai Li, Zhao Li, Chunxue Wang, Yifei Liang, Yatong Pang in Nature Communications (2024)

  9. Article

    Open Access

    Association between exposure to ambient air pollution, meteorological factors and atopic dermatitis consultations in Singapore—a stratified nationwide time-series analysis

    Atopic dermatitis (AD) is a chronic inflammatory skin disease affecting approximately 20% of children globally. While studies have been conducted elsewhere, air pollution and weather variability is not well st...

    Diyar Mailepessov, Janet Ong, Muhammad Zafir Mohamad Nasir, Joel Aik in Scientific Reports (2024)

  10. No Access

    Article

    Long-range order enabled stability in quantum dot light-emitting diodes

    Light-emitting diodes (LEDs) based on perovskite quantum dots (QDs) have produced external quantum efficiencies (EQEs) of more than 25% with narrowband emission1,2, but these LEDs have limited operating lifetimes...

    Ya-Kun Wang, Haoyue Wan, Sam Teale, Luke Grater, Feng Zhao, Zhongda Zhang in Nature (2024)

  11. Article

    Open Access

    An artificial visual neuron with multiplexed rate and time-to-first-spike coding

    Human visual neurons rely on event-driven, energy-efficient spikes for communication, while silicon image sensors do not. The energy-budget mismatch between biological systems and machine vision technology has...

    Fanfan Li, Dingwei Li, Chuanqing Wang, Guolei Liu, Rui Wang in Nature Communications (2024)

  12. Article

    Open Access

    Upgrading CO2 to sustainable aromatics via perovskite-mediated tandem catalysis

    The directional transformation of carbon dioxide (CO2) with renewable hydrogen into specific carbon-heavy products (C6+) of high value presents a sustainable route for net-zero chemical manufacture. However, it i...

    Guo Tian, Zhengwen Li, Chenxi Zhang, **nyan Liu, **aoyu Fan in Nature Communications (2024)

  13. Article

    Open Access

    Advancing high-performance visible light communication with long-wavelength InGaN-based micro-LEDs

    This study showcases a method for achieving high-performance yellow and red micro-LEDs through precise control of indium content within quantum wells. By employing a hybrid quantum well structure with our six ...

    Fu-He Hsiao, Wen-Chien Miao, Tzu-Yi Lee, Yi-Hua Pai, Yu-Ying Hung in Scientific Reports (2024)

  14. Article

    Open Access

    Predictive evolutionary modelling for influenza virus by site-based dynamics of mutations

    Influenza virus continuously evolves to escape human adaptive immunity and generates seasonal epidemics. Therefore, influenza vaccine strains need to be updated annually for the upcoming flu season to ensure v...

    **gzhi Lou, Weiwen Liang, Lirong Cao, Inchi Hu, Shi Zhao in Nature Communications (2024)

  15. Article

    Open Access

    Neoadjuvant–adjuvant pertuzumab in HER2-positive early breast cancer: final analysis of the randomized phase III PEONY trial

    The randomized, multicenter, double-blind, placebo-controlled, phase III PEONY trial (NCT02586025) demonstrated significantly improved total pathologic complete response (primary endpoint) with dual HER2 block...

    Liang Huang, Da Pang, Hongjian Yang, Wei Li, Shusen Wang in Nature Communications (2024)

  16. Article

    Open Access

    Multicenter study of seasonal and regional airborne allergens in Chinese preschoolers with allergic rhinitis

    This study is nationwide multicenter epidemiological research, aimed at investigating the distribution changes and seasonal patterns of various airborne allergens among preschool children with allergic rhiniti...

    Zhifeng Huang, Aoli Li, Huiqing Zhu, Junxiu Pan, Jun **ao, Jiang Wu in Scientific Reports (2024)

  17. Article

    Open Access

    Ocular microvascular alteration in patients with myocardial infarction—a new OCTA study

    Myocardial infarction is defined as a sudden decrease or interruption in blood flow to the coronary arteries, causing ischemic necrosis of the corresponding cardiomyocytes. It is unclear whether systemic macro...

    Jun-Yi Wu, **-Yu Hu, Qian-Min Ge, San-Hua Xu, Jie Zou, Min Kang in Scientific Reports (2024)

  18. Article

    Open Access

    Harmonic amide bond density as a game-changer for deciphering the crosslinking puzzle of polyamide

    It is particularly essential to analyze the complex crosslinked networks within polyamide membranes and their correlation with separation efficiency for the insightful tailoring of desalination membranes. Howe...

    Yu-Ren Xue, Chang Liu, Zhao-Yu Ma, Cheng-Ye Zhu, Jian Wu in Nature Communications (2024)

  19. Article

    Open Access

    Continuous and discontinuous compressible flows in a converging–diverging channel solved by physics-informed neural networks without exogenous data

    Physics-informed neural networks (PINNs) are employed to solve the classical compressible flow problem in a converging–diverging nozzle. This problem represents a typical example described by the Euler equatio...

    Hong Liang, Zilong Song, Chong Zhao, **n Bian in Scientific Reports (2024)

  20. No Access

    Article

    Flexible silicon solar cells with high power-to-weight ratios

    Silicon solar cells are a mainstay of commercialized photovoltaics, and further improving the power conversion efficiency of large-area and flexible cells remains an important research objective1,2. Here we repor...

    Yang Li, **aoning Ru, Miao Yang, Yuhe Zheng, Shi Yin, Chengjian Hong, Fuguo Peng in Nature (2024)

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