29 Result(s)
within
Medicine & Public Health
Pneumology/Respiratory System
Hong-** Liang
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Article
Free Papers
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Article
Heart rate-corrected QT interval and QT dispersion in patients with pulmonary hypertension
OBJECTIVE: Heart rate-corrected QT interval (QTc) and QTc dispersion (QTcd) are increased and associated with ventricular arrhythmia and an increase in sudden death in a variety of diseases. This study aimed t...
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Article
Effects of continuous positive airway pressure on blood pressure and daytime sleepiness in obstructive sleep apnea patients with coronary heart diseases under optimal medications
Continuous positive airway pressure (CPAP) is an effective therapy for obstructive sleep apnea (OSA). However, for patients who already have OSA and coronary heart diseases (CHD) with optimal medications, whet...
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Use of SPECT to detect changes in diastolic and coronary reserve in patients with obstructive sleep apnea
To assess diastolic function and coronary artery reserve in patients with obstructive sleep apnea (OSA) using single-photon emission computer tomography (SPECT).
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Article
The prevalence and associated risk factors of sleep disorder-related symptoms in pregnant women in China
The sleep disorder in pregnant women remains unfamiliar to perinatal care providers, resulting in lack of appropriate care. This study was designed to investigate the prevalence of sleep disorder-related sympt...
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Open AccessmAChRs activation induces epithelial-mesenchymal transition on lung epithelial cells
Epithelial-mesenchymal transition (EMT) has been proposed as a mechanism in the progression of airway diseases and cancer. Here, we explored the role of acetylcholine (ACh) and the pathway involved in the proc...
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Relationship between surfactant proteins B and C and obstructive sleep apnea: is serum SP-B concentration a potential biomarker of obstructive sleep apnea?
Surfactant proteins B and C are mainly synthesized, secreted by alveolar type II cells, and affected by hypoxia and mechanical stretches. We hypothesized that their serum levels might be altered by intermitten...
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Open AccessThe activation of M3 mAChR in airway epithelial cells promotes IL-8 and TGF-β1 secretion and airway smooth muscle cell migration
Muscarinic acetylcholine receptors (mAChRs) have been identified in airway epithelium, and epithelium-derived chemokines can initiate the migration of airway smooth muscle (ASM) cells. However, the mAChRs that...
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Open AccessThe efficacy of initial ventilation strategy for adult immunocompromised patients with severe acute hypoxemic respiratory failure: study protocol for a multicentre randomized controlled trial (VENIM)
Acute respiratory failure (ARF) is still one of the most severe complications in immunocompromised patients. Our previous systematic review showed noninvasive mechanical ventilation (NIV) reduced mortality, le...
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Open AccessIL-4-induced caveolin-1-containing lipid rafts aggregation contributes to MUC5AC synthesis in bronchial epithelial cells
Mucus overproduction is an important feature of asthma. Interleukin (IL)-4 is required for allergen-induced airway inflammation and mucus production. MUC5AC gene expression is regulated by transcript factors N...
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Open AccessPM2.5 promotes human bronchial smooth muscle cell migration via the sonic hedgehog signaling pathway
The contribution of airway remodeling in chronic obstructive pulmonary disease (COPD) has been well documented, with airway smooth muscle cell proliferation and migration playing a role in the remodeling proce...
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Influences of obstructive sleep apnea on blood pressure variability might not be limited only nocturnally in middle-aged hypertensive males
In this cross-sectional study, we analyzed the potential association between sleep measures and blood pressure variability.
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Open AccessScored minor criteria for severe community-acquired pneumonia predicted better
Infectious Disease Society of America/American Thoracic Society (IDSA/ATS) minor criteria for severe community-acquired pneumonia (CAP) are of unequal weight in predicting mortality, but the major problem asso...
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Open AccessCorrection to: Scored minor criteria for severe community-acquired pneumonia predicted better
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Open AccessThe characteristics of the frequent exacerbator with chronic bronchitis phenotype and non-exacerbator phenotype in patients with chronic obstructive pulmonary disease: a meta-analysis and system review
Chronic obstructive pulmonary disease (COPD) patients with different phenotypes show different clinical characteristics. Therefore, we conducted a meta-analysis to explore the clinical characteristics between ...
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Open AccessCold-inducible RNA-binding protein might determine the severity and the presences of major/minor criteria for severe community-acquired pneumonia and best predicted mortality
Severity of community-acquired pneumonia (CAP) depends on microbial pathogenicity, load and virulence, and immune responses. The Infectious Disease Society of America and the American Thoracic Society (IDSA/AT...
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Chapter
Obstructive Pulmonary Disease
Patients with obstructive pulmonary diseases, mainly including chronic obstructive pulmonary disease (COPD) and asthma, compromise a considerable proportion of mechanically ventilated patients in the intensive...
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Chapter
Ventilator-Induced Diaphragm Dysfunction
It was Vassilakopoulos and Petrof who first proposed the concept of ventilator-induced diaphragm dysfunction (VIDD) in 2004, which refers to the loss of diaphragmatic force-generating capacity that is specific...
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Chapter
Extravascular Lung Water Monitoring
Water contributes 80% of the lung components; however, most of them existed in the blood vessels and distributed in a gradient of increasing density from nondependent to dependent regions. By definition, extra...
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Noninvasive Ventilation
Noninvasive ventilation (NIV) refers to mechanical ventilation without invasive artificial airways. There have been many noninvasive methods of assisted ventilation in the past, including negative pressure ven...
