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  1. Article

    Open Access

    Waning humoral immune responses to inactivated SARS-CoV-2 vaccines in patients with severe liver disease

    Zhiwei Chen, Yingzhi Zhang, Rui Song, Lu Wang in Signal Transduction and Targeted Therapy (2022)

  2. Article

    Open Access

    Bimodular effects of D614G mutation on the spike glycoprotein of SARS-CoV-2 enhance protein processing, membrane fusion, and viral infectivity

    **aoyi Jiang, Zhengrong Zhang, Chenxi Wang in Signal Transduction and Targeted Therapy (2020)

  3. Article

    Open Access

    Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

    Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARH) control energy homeostasis by sensing hormonal and nutrient cues and activating secondary melanocortin sensing neurons. We id...

    Austin M. Reilly, Shudi Zhou, Sunil K. Panigrahi, Shijun Yan in Nutrition & Diabetes (2019)

  4. Article

    Open Access

    Spatiotemporal variations in cardiovascular disease mortality in China from 1991 to 2009

    In China, the spatiotemporal variations in cardiovascular disease (CVD) mortality are seldom characterized to understand their epidemiological features. It would be helpful to evaluate the performance of CVD-r...

    Hongyan Ren, **a Wan, Cao Wei, Gonghuan Yang in BMC Cardiovascular Disorders (2019)

  5. Article

    Open Access

    Curcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function

    Antioxidants have shown great promise in stroke prevention. Diarylheptanoids (also known as diphenylheptanoids) are a small class of plant secondary metabolites that possess antioxidant activity greater than t...

    Cong Lan, **njian Chen, Yuxun Zhang, Wei Wang in BMC Cardiovascular Disorders (2018)

  6. Article

    Activation of angiotensin II type 1 receptors increases D4 dopamine receptor expression in rat renal proximal tubule cells

    Both the dopaminergic and renin–angiotensin systems play important roles in the regulation of blood pressure. Our previous study showed that the stimulation of dopaminergic D4 receptors reduced angiotensin II typ...

    Luxun Tang, Shuo Zheng, Hongmei Ren, Duofen He, Chunyu Zeng in Hypertension Research (2017)

  7. Article

    D3 dopamine receptor regulation of D5 receptor expression and function in renal proximal tubule cells

    Dopamine receptor, via D1-like and D2-like receptors, increases sodium excretion in kidney. We have reported positive interactions between D3 and D1 receptors in renal proximal tubule (RPT) cells. These reports, ...

    Hefei Huang, Hongmei Ren, Caiyu Chen, **aoyan Wang, Jian Yang in Hypertension Research (2012)

  8. Article

    Role of Gα12- and Gα13-protein subunit linkage of D3 dopamine receptors in the natriuretic effect of D3 dopamine receptor in kidney

    The D3 dopamine receptor is the major D2-like receptor that regulates sodium transport in the renal proximal tubule (RPT) and helps maintain blood pressure in the normal range. In Wistar–Kyoto (WKY) rats chronica...

    Ye Zhang, Chunjiang Fu, Laureano D Asico, Van Anthony M Villar in Hypertension Research (2011)

  9. Article

    Inhibitory effect of ETB receptor on Na+–K+ ATPase activity by extracellular Ca2+ entry and Ca2+ release from the endoplasmic reticulum in renal proximal tubule cells

    The kidney is important in the long-term regulation of blood pressure and sodium homeostasis. Stimulation of ETB receptors in the kidney increases sodium excretion, in part, by decreasing sodium transport in t...

    Yan Liu, Jian Yang, Hongmei Ren, Duofen He, Annabelle Pascua in Hypertension Research (2009)