![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessWaning humoral immune responses to inactivated SARS-CoV-2 vaccines in patients with severe liver disease
-
Article
Open AccessBimodular effects of D614G mutation on the spike glycoprotein of SARS-CoV-2 enhance protein processing, membrane fusion, and viral infectivity
-
Article
Open AccessGpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding
Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARH) control energy homeostasis by sensing hormonal and nutrient cues and activating secondary melanocortin sensing neurons. We id...
-
Article
Open AccessSpatiotemporal variations in cardiovascular disease mortality in China from 1991 to 2009
In China, the spatiotemporal variations in cardiovascular disease (CVD) mortality are seldom characterized to understand their epidemiological features. It would be helpful to evaluate the performance of CVD-r...
-
Article
Open AccessCurcumin prevents strokes in stroke-prone spontaneously hypertensive rats by improving vascular endothelial function
Antioxidants have shown great promise in stroke prevention. Diarylheptanoids (also known as diphenylheptanoids) are a small class of plant secondary metabolites that possess antioxidant activity greater than t...
-
Article
Activation of angiotensin II type 1 receptors increases D4 dopamine receptor expression in rat renal proximal tubule cells
Both the dopaminergic and renin–angiotensin systems play important roles in the regulation of blood pressure. Our previous study showed that the stimulation of dopaminergic D4 receptors reduced angiotensin II typ...
-
Article
D3 dopamine receptor regulation of D5 receptor expression and function in renal proximal tubule cells
Dopamine receptor, via D1-like and D2-like receptors, increases sodium excretion in kidney. We have reported positive interactions between D3 and D1 receptors in renal proximal tubule (RPT) cells. These reports, ...
-
Article
Role of Gα12- and Gα13-protein subunit linkage of D3 dopamine receptors in the natriuretic effect of D3 dopamine receptor in kidney
The D3 dopamine receptor is the major D2-like receptor that regulates sodium transport in the renal proximal tubule (RPT) and helps maintain blood pressure in the normal range. In Wistar–Kyoto (WKY) rats chronica...
-
Article
Inhibitory effect of ETB receptor on Na+–K+ ATPase activity by extracellular Ca2+ entry and Ca2+ release from the endoplasmic reticulum in renal proximal tubule cells
The kidney is important in the long-term regulation of blood pressure and sodium homeostasis. Stimulation of ETB receptors in the kidney increases sodium excretion, in part, by decreasing sodium transport in t...