23 Result(s)

Article

Functional analysis of three novel cell lines derived from human papillary thyroid carcinomas with three different clinical courses

Papillary thyroid carcinoma (PTC) is the most frequent thyroid carcinoma. PTC cell lines have been of considerable value in studying aspects of thyroid cancer, such as gene expression, cell proliferation, and ...

Mayumi Ishikawa, Toshiaki Tachibana, Hisashi Hashimoto, Junko Toyomura… in Human Cell (2014)

Article

Novel functional hepatocyte cell line derived from spontaneous dwarf rat: Model of growth hormone function in vitro

Currently there is no good hepatocyte model for studying growth hormone (GH) function that reflects its normal physiological roles. Here we report the establishment of a functional hepatocyte cell line, SDRL-1...

Mayumi Ishikawa, Toshiaki Tachibana, Gen Yoshino, Hisashi Hashimoto… in Human Cell (2010)

Article

Establishment and characterization of a novel cell line derived from a human small cell lung carcinoma that secretes parathyroid hormone, parathyroid hormone-related protein, and pro-opiomelanocortin

There are few case reports describing small cell lung carcinoma (SCLC), which secrete parathyroid hormone (PTH)-related protein (PTHrP) and result in hypercalcemia. We have established a novel cell line, deriv...

Mayumi Ishikawa, Kazuhiro Kimura, Toshiaki Tachibana, Hisashi Hashimoto… in Human Cell (2010)

Article

Establishment and characterization of HER2-positive cell line derived from pleural effusion of human breast scirrhous carcinoma

We have established a cell line derived from a pleural effusion of breast scirrhous carcinoma. This cell line presented immunohistochemically negative for estrogen receptor and slightly positive for progestero...

Isao Tabei, Shigeki Nishiyama, Shigeo Yamashita, Hisashi Hashimoto… in Human Cell (2008)

Article

Establishment and characterization of a cell line (IGSK-3) secreting human chorionic gonadotropin, adrenocorticotropic hormone and parathyroid hormone-related protein derived from primary poorly differentiated adenocarcinoma of the stomach

We recently established human chorionic gonadotropin-, adrenocorticotropic hormone- and parathyroid hormone-related protein-secreting cell line derived from primary poorly differentiated adenocarcinoma of the ...

Shigeo Yamashita, Naoto Takahashi, Hisashi Hashimoto, Toshiaki Tachibana… in Human Cell (2008)

Article

Establishment and characterization of a human cell line derived from a uterine papillary serous carcinoma with wild-type p53 function

Uterine papillary serous carcinoma is an uncommon histologic subtype of endometrial cancer that behaves aggressively and has a poor prognosis. We successfully established a uterine papillary serous carcinoma c...

Hisashi Hashimoto, Atsumi Kojima, Tamotsu Sudo, Noriyoshi Ohki… in Human Cell (2008)

Article

Establishment and characterization of a cell line (BTIC) including HER-2-positive cells derived from pleural effusion of recurrent breast invasive ductal carcinoma, scirrhous type

Human epidermal growth factor receptor-2 (HER-2) overexpression in breast cancer occurs in 20% to 30% of patients with breast cancer. Trastuzumab (Herceptin) targets HER-2 tyrosine kinase receptors expressed o...

Kouzou Ninomiya, Satoshi Ohi, Isao Tabei, Song **, Toshiaki Tachibana… in Human Cell (2007)

Article

Establishment and characterization of an IGSK-2 cell line derived from ascitic fluid of recurrent hCG and somatostatin secreted adenocarcinoma of the stomach

We examined a 32-year-old Japanese man who was clinically diagnosed with gastric cancer, type 4, and histopathologically diagnosed with mucinous and poorly differentiated adenocarcinoma (mucinous > poorly) of ...

Satoshi Ohi, Naoto Takahashi, Hisashi Hashimoto, Toshiaki Tachibana… in Human Cell (2007)

Article

Establishment and characterization of a cisplatin-resistant cell line (IGSK-1) from a poorly differentiated gastric adenocarcinoma

We successfully established a spontaneously cisplatin-resistant tumor cell line (designated as IGSK-1) derived from original gastric carcinoma. The patient was a 75-year-old Japanese woman. The histopathologic...

Satoshi Ohi, Naoto Takahashi, Kouzou Ninomiya, Masako Nakajima… in Human Cell (2007)

Article

Establishment and characterization of a cell line (NABCA) derived from metastatic lymph nodes of breast scirrhous carcinoma

We successfully established a breast scirrhous carcinoma cell line (designated as NABCA) derived from metastatic tumors of the lymph node. The cells grew as multi-layered cultures without contact inhibition. T...

Satoshi Ohi, Shigeya Kyoda, Isao Tabei, Kouzou Ninomiya, Kayoko Sugiyama… in Human Cell (2006)

Article

Proliferation and tube formation of periodontal endothelial cells

Angiogenesis is indispensable to guide a regeneration of good periodontal tissue in the wound healing after periodontal surgery. Hepatocyte growth factor is well known for a strong angiogenic factor and it may...

Etsuko Sato, Hisashi Hashimoto, Hisahiro Kamoi, Toshiaki Tachibana… in Human Cell (2005)

Article

Abstract of Poster Presentation

Hiroshi Uchida, Tetsuo Maruyama, Jkuko Sugiura, Takashi Kajitani, Touru Arase… in Human Cell (2005)

Article

Establishment and characterization of a human malignant choroids plexus papilloma cell line (HIBCPP)

A cell line designated “HIBSPP” was established from a human malignant choroids plexus papilloma of 29-year-old Japanese woman. This line grew well without interruption for 3 years and was subcultivated over 7...

Isamu Ishiwata, Chieko Ishiwata, Emiko Ishiwata, Yoshiro Sato… in Human Cell (2005)

Article

Establishment and characterization of EB virus-free normal B-lymphocyte and interleukin-6-producing poorly differentiated adenocarcinoma cell lines derived from gastric tumor tissue

We successfully established two cell lines, an adenocarcinoma cell line (designated as HIGS) and Epstein-Barr virus-free normal B-lymphocyte cell line (designated as HIGS-BL), derived from a moderately to poor...

Satoshi Ohi, Hisashi Hashimoto, Toshiaki Tachibana, Isao Tabei… in Human Cell (2005)

Article

Establishment and characterization of a human ovarian small cell carcinoma, hypercalcemic type, cell line (OS-1) secreting PTH, PTHrP and ACTH-special reference to the susceptibility of anti-cancer drugs-

We successfully established a novel cell line (OS-1) derived from human ovarian small cell carcinoma, hypercalcemic type secreted PTH, PTH-rP and ACTH. The OS-1 cell line was established from metastatic focus ...

Satoshi Ohi, Shigeki Niimi, Naoya Okada, Kyosuke Yamada, Toshiaki Tachibana… in Human Cell (2004)

Article

Abstracts of Poster Presentations

Megumi Iguchi, Isamu Ishiwata, Tomoharu Tamagawa, Chieko Ishiwata… in Human Cell (2004)

Article

Establishment and characterization of a nerve cell line (NC-HIMT) from HIMT cells derived from a human ovarian immature teratoma with special reference to the induction of neuron differentiation by retinoic acid

A nerve cell line designated NC-HIMT was established from a HIMT cell line derived from a benign ovarian, three germ layer immature teratoma removed from a 21-year-old Japanese female. The HIMT cells were elon...

Takashi Yokose, Hisashi Hashimoto, Toshiaki Tachibana, Satoshi Ohi… in Human Cell (2004)

Article

Establishment and characterization of a human gestational choriocarcinoma cell line (HOCC)

Human gestational choriocarcinoma cell line (HOCC) was established from the mouse graft of choriocarcinorna. The HOCC cells were spindle or polygonal in shape and multi-nucleated giant cells, showing neoplasti...

Isamu Ishiwata, Chieko Ishiwata, Akira Tsuiki, Kazushige Kiguchi… in Human Cell (2004)

Article

New method for forming large embryoid bodies using the wall of the culture dish along with an analysis of their structural characteristics

Early embryonic stem (EES) cells, which were established from 2 cell stage embryos obtained from ddY mice, had similar characteristics as embryonic stem (ES) cells. These cells were maintained in an undifferen...

Motoyoshi Yamamoto, Hisashi Hashimoto, Toshiaki Tachibana, Satoshi Ohi… in Human Cell (2004)

Article

The differentiation of early embryonic stem cells into adipocytes-like cells

An early embryonic stem cell line, EES-6 cells, was established fiom 2-cell stage embryos of ddY mice. The cells were maintained in an undifferentiated state with D-MEM/FlZ medium supplemented with 10% fetal b...

Motoyoshi Yamamoto, Toshiaki Tachibana, Hisashi Hashimoto, Isamu Ishiwata… in Human Cell (2003)