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  1. No Access

    Article

    Atezolizumab addition to platinum doublet: evaluating survival outcomes for patients with extensive disease small cell lung cancer

    The efficacy of adding atezolizumab to the platinum doublet regimen for extensive disease small cell lung cancer (ED-SCLC) remains marginally limited.

    Sousuke Kubo, Nobuaki Kobayashi in Journal of Cancer Research and Clinical On… (2023)

  2. Article

    Open Access

    Immune activation during the implantation phase causes preeclampsia-like symptoms via the CD40–CD40 ligand pathway in pregnant mice

    The CD40 ligand (CD40L) is expressed by T cells and has a critical role in immune system regulation. Interventions targeting CD40L interactions following embryo implantation represent an approach to preventing...

    Keiichi Matsubara, Yuko Matsubara, Miki Mori, Yuka Uchikura in Hypertension Research (2016)

  3. Article

    Open Access

    Detection of vitellogenin incorporation into zebrafish oocytes by FITC fluorescence

    Large volumes of lymph can be collected from the eye-sacs of bubble-eye goldfish. We attempted to induce vitellogenin (Vtg) in the eye-sac lymph of bubble-eye goldfish and develop a method for visualizing Vtg ...

    Yohei Matsuda, Yoshie Ito, Hisashi Hashimoto in Reproductive Biology and Endocrinology (2011)

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    Article

    Apoptosis in the small intestine of neonatal rat using blue light-emitting diode devices and conventional halogen-quartz devices in phototherapy

    Phototherapy is the most frequently used treatment for the neonatal jaundice. However, recent papers report that phototherapy increased apoptosis in peripheral mononuclear leukocytes in vivo and in mouse lymph...

    Keiichiro Tanaka, Hisashi Hashimoto, Toshiaki Tachibana in Pediatric Surgery International (2008)

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    Article

    Effect of tumour angiogenesis factor on proliferation of endothelial cell and tube formation

    The effect of a tumour angiogenesis factor on proliferation of various kinds of cells was examined in vitro. The factor (TAF) a polypeptide of 14000 molecular weight, was extracted and purified from the condit...

    Isamu Ishiwata, Chieko Ishiwata, Masayuki Soma, Dhurba Raj Naik in Virchows Archiv A (1990)

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    Article

    Effects of prolactin during preincubation of mouse spermatozoa on fertilizing capacity in vitro

    In the present study, some beneficial effects of mouse prolactin (PRL) on spermatozoa were demonstrated in mice. The motility rate of spermatozoa is well maintained during incubation in modified Krebs-Ringer b...

    Aisaku Fukuda, Chisato Mori in Journal of in Vitro Fertilization and Embr… (1989)

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    Article

    Influences of prolactin upon spermatogenesis and spermatozoa during in vitro fertilization in mice

    Hyperprolactinemia, induced by pituitary isografts for 20 weeks in male mice and confirmed by radioimmunoassay using anti-mouse prolactin serum, did not impair spermatogenesis in the testis and maturing proces...

    Chisato Mori, Hisashi Hashimoto in Journal of in Vitro Fertilization and Embr… (1988)

  8. No Access

    Article

    Effects of prolactin on gametes and zygotes during in vitro fertilization in mice

    Hyperprolactinemia is one of the major causative factors of infertility. However, the effect of prolactin on gametes during in vitro fertilization has not been elucidated. In the present study, the effects of ...

    Aisaku Fukuda, Yoichi Noda, Takahide Mori in Journal of in Vitro Fertilization and Embr… (1988)