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Article
Aortic valve area index values of Trifecta implants correlate with energy loss and increased valve stress
Biological valves are becoming more frequently used in aortic valve replacement. While several reports have evaluated the performance of biological valves, echocardiography studies during exercise stress remai...
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Article
Twisting of HeartMate II outflow graft 2.5 years after implantation–HM2 is still ongoing
A 47-year-old woman with dilated cardiomyopathy underwent HeartMate II (HM2) implantation as a bridge-to-transplantation. Her postoperative course was good. However, 2.5 years after surgery, the outflow graft ...
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Article
Open AccessSecond-line immunosuppressant administration for steroid-refractory immune-related adverse events in patients with lung cancer
Evidence for use of second-line immunosuppressants for immune-related adverse events (irAEs) is inadequate. Therefore, a multicenter analysis should assess the efficacy of second-line immunosuppressants for se...
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Article
Surgery for spina bifida occulta: spinal lipoma and tethered spinal cord
The technical evolution of the surgery for spina bifida occulta (SBO) over the course of a half-century was reviewed with special foci placed on the spinal lipoma and tethered spinal cord. Looking back through...
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Article
Open AccessOne-dimensional array of nanoparticles using segmented polyurethane nanofibers as a template for enhanced catalytic efficiency
Metal nanoparticles are used to catalyze chemical reactions. Among them, noble metal nanoparticle catalysts need to be used in small quantities. Some reports reveal catalytic activity is further improved by co...
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Article
Soluble interleukin-2 receptor as a predictive biomarker for poor efficacy of combination treatment with anti-PD-1/PD-L1 antibodies and chemotherapy in non-small cell lung cancer patients
Soluble interleukin-2 receptor (sIL-2R) suppresses effector T-cells. Few studies have assessed serum sIL-2R in patients receiving immunotherapy. We evaluated the association between serum sIL-2R levels and the...
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Article
Total arch replacement with both frozen elephant trunk and transthoracic aorto-axillary extra-anatomical bypass through partial sternotomy for acute aortic dissection in a tracheostomy patient
Median sternotomy near an existing tracheostoma risks deep sternal wound infection after cardiac surgery. We present herein a case of acute type A aortic dissection in a patient with a permanent tracheostoma a...
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Article
Two cases of catastrophic deterioration and multiple leaflet detachment in Trifecta valves
Reports of early and catastrophic acute structural valve deterioration (SVD) in Trifecta valve (Abbott, St Paul, MN, USA) with multiple leaflet detachment are rare. We encountered two cases of early SVD in Tri...
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Article
Electrochemical characteristics of a gold nanoparticle-modified controlled enzyme–electrode contact junction electrode
Biodevices in which biomolecules such as enzymes and antibodies are immobilized on the surface of electrode materials are capable of converting chemical energy into electrical energy, and are expected to contr...
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Article
The effect of roller head pump on platelet deterioration during the simulated extracorporeal circulation
Roller pum** results in hemolysis and adverse effects on coagulation, but there are few reports on the influence of roller heads on platelets. Here, we evaluate the interaction between roller pum** and pla...
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Article
Site-Directed Mutagenesis of Multicopper Oxidase from Hyperthermophilic Archaea for High-Voltage Biofuel Cells
Enzymes from hyperthermophilic archaea are potential candidates for industrial use because of their superior pH, thermal, and long-term stability, and are expected to improve the long-term stability of biofuel...
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Article
Open AccessProcalcitonin expression in patients with large cell neuroendocrine carcinoma of the lung
Procalcitonin (PCT) has received much attention as a serum marker for bacterial infection. Elevated serum PCT is occasionally seen in severe trauma, heatstroke, and neoplastic diseases, including lung cancer w...
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Article
Open AccessDissociated responses at initial computed tomography evaluation is a good prognostic factor in non-small cell lung cancer patients treated with anti-programmed cell death-1/ligand 1 inhibitors
Dissociated responses (DR) are phenomena in which some tumors shrink, whereas others progress during treatment of patients with cancer. The purpose of the present study was to evaluate the frequency and progno...
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Article
Adaptation for Mitigation
This paper develops a two-region (North and South) dynamic model in which regional stocks of effective labor are negatively influenced by the global stock of pollution. By characterizing the equilibrium strate...
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Article
Open AccessNarrowing down the region responsible for 1q23.3q24.1 microdeletion by identifying the smallest deletion
Interstitial deletions of 1q23.3q24.1 are rare. Here, chromosomal microarray testing identified a de novo microdeletion of arr[GRCh37]1q23.3q24.1(164816055_165696996) × 1 in a patient with moderate development...
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Article
A long-term survivor of pediatric midline glioma with H3F3A K27M and BRAF V600E double mutations
We report a case of 2-year-old female with lateral ventricular glioma harboring both H3F3A K27M and BRAF V600E mutations. By the methylation analysis, the tumor was classified as a diffuse midline glioma H3 K27M ...
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Article
Open AccessAlterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
Infant gliomas have paradoxical clinical behavior compared to those in children and adults: low-grade tumors have a higher mortality rate, while high-grade tumors have a better outcome. However, we have little...
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Article
Open AccessReal-world study of afatinib in first-line or re-challenge settings for patients with EGFR mutant non-small cell lung cancer
Afatinib, a second-generation epidermal growth factor receptor (EGFR)—tyrosine kinase inhibitor (TKI) for mutant non-small cell lung cancer (NSCLC), was approved in Japan in 2014. This study evaluated clinical...
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Article
Open AccessType D personality is a predictor of prolonged acute brain dysfunction (delirium/coma) after cardiovascular surgery
Previous studies have shown a relationship between delirium and depressive symptoms after cardiac surgery with distress personalities linking to negative surgical outcomes. The aim of the present study is to f...
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Article
Author Correction: Effect of polymer type on the performance of a nanofiber mat actuator
In the original published version of Table 1 and Table S1, the conductivity values are incorrect. The corrected Tables are as shown below.