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  1. Article

    Open Access

    A novel test for type-I allergy based on crosslink formation of immunoglobulin-E receptors by allergen-specific immunoglobulin-E antibodies and an allergen

    Detection of allergen-specific immunoglobulin E (IgE) antibodies (Abs) in serum would allow for screening of the causative allergen in patients with type-I allergy. In this study, we developed a new assay meth...

    Yuki Koga, Soichiro Ishii, Tomoharu Yokooji, Konomi Yamamoto in Scientific Reports (2023)

  2. Article

    Open Access

    Influence of discontinuation of prophylactic antimicrobial agent for trabeculectomy

    There is no unified view of the necessity of prophylactic antimicrobial agents in trabeculectomy. Preoperative prophylactic antimicrobial agent injection and cefazolin sodium (CEZ) for trabeculectomy were disc...

    Yuuka Ushio, Hiroshi Yoshikawa in Journal of Pharmaceutical Health Care and … (2023)

  3. Article

    Open Access

    Identification of allergens for food-dependent exercise-induced anaphylaxis to shrimp

    Shrimp is a causative food that elicits food-dependent exercise-induced anaphylaxis (FDEIA). In this study, we sought to identify IgE-binding allergens in patients with shrimp-FDEIA. Sera were obtained from ei...

    Shiori Akimoto, Tomoharu Yokooji, Ryohei Ogino, Yuko Chinuki in Scientific Reports (2021)

  4. Article

    Open Access

    Impact of systemic steroid treatment on talc pleurodesis: a report of six cases

    Instillation of sterile graded talc in the pleural space is performed to prevent reaccumulation of malignant pleural effusion after drainage. Talc is thought to encourage pleural adhesions as part of the repai...

    Soichiro Ishii, Hiroshi Sakurashita in Journal of Pharmaceutical Health Care and … (2020)

  5. Article

    Open Access

    Blockade of multiple monoamines receptors reduce insulin secretion from pancreatic β-cells

    Clinical use of olanzapine frequently causes severe hyperglycemia as an adverse effect. In this study, we elucidated mechanisms by which olanzapine reduced insulin secretion using the hamster pancreatic β-cell...

    Mao Nagata, Tomoharu Yokooji, Tomoe Nakai, Yumika Miura in Scientific Reports (2019)

  6. Article

    Open Access

    Investigating interindividual variations in cortical bone quality: analysis of the morphotypes of secondary osteons and their population densities in the human femoral diaphysis

    Osteons are the primary sites of cortical bone lesions. However, many aspects of osteon microstructure remain poorly understood. This study aimed to explores interindividual differences in the osteon morphotyp...

    Hiroaki Matsuo, Toshiyuki Tsurumoto, Junichiro Maeda in Anatomical Science International (2019)

  7. Article

    Open Access

    XXIV World Allergy Congress 2015

    A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

    Heung-Man Lee, Il-Ho Park, Jae-Min Shin in World Allergy Organization Journal (2016)

  8. No Access

    Article

    Usability of Fag e 2 ImmunoCAP in the diagnosis of buckwheat allergy

    Currently, the detection of crude buckwheat extract-specific IgE by ImmunoCAP (f11) (Phadia AB, Uppsala, Sweden) is widely used to diagnose buckwheat allergy. However, the results of this test do not always co...

    Kimiko Tohgi, Kunie Kohno, Hitoshi Takahashi in Archives of Dermatological Research (2011)

  9. No Access

    Article

    Difference in the stable nitrogen isotope ratio of Sargassum piluliferum (Phaeophyceae: Fucales) associated with fish and pearl oyster aquaculture facilities

    In order to estimate the nitrogen loading from fish aquaculture facilities, we studied the nitrogen and carbon stable isotope ratios (δ15N and δ13C, respectively) in the brown macroalga Sargassum piluliferum and ...

    Hiroaki Matsuo, Nobuyuki Matsuka, Koji Omori, Yoshitsugu Koizumi in Fisheries Science (2010)

  10. No Access

    Article

    Increased production of vascular endothelial growth factor in the lesions of atopic dermatitis

    Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by severe itching, erythema and edema resistant to anti-histamine therapy. Vascular endothelial growth factor (VEGF) is a potent agen...

    Yan Zhang, Hiroaki Matsuo, Eishin Morita in Archives of Dermatological Research (2006)