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  1. Article

    Open Access

    A novel test for type-I allergy based on crosslink formation of immunoglobulin-E receptors by allergen-specific immunoglobulin-E antibodies and an allergen

    Detection of allergen-specific immunoglobulin E (IgE) antibodies (Abs) in serum would allow for screening of the causative allergen in patients with type-I allergy. In this study, we developed a new assay meth...

    Yuki Koga, Soichiro Ishii, Tomoharu Yokooji, Konomi Yamamoto in Scientific Reports (2023)

  2. Article

    Open Access

    Identification of allergens for food-dependent exercise-induced anaphylaxis to shrimp

    Shrimp is a causative food that elicits food-dependent exercise-induced anaphylaxis (FDEIA). In this study, we sought to identify IgE-binding allergens in patients with shrimp-FDEIA. Sera were obtained from ei...

    Shiori Akimoto, Tomoharu Yokooji, Ryohei Ogino, Yuko Chinuki in Scientific Reports (2021)

  3. Article

    Open Access

    Blockade of multiple monoamines receptors reduce insulin secretion from pancreatic β-cells

    Clinical use of olanzapine frequently causes severe hyperglycemia as an adverse effect. In this study, we elucidated mechanisms by which olanzapine reduced insulin secretion using the hamster pancreatic β-cell...

    Mao Nagata, Tomoharu Yokooji, Tomoe Nakai, Yumika Miura in Scientific Reports (2019)