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  1. Article

    Open Access

    Drug reinforcement impairs cognitive flexibility by inhibiting striatal cholinergic neurons

    Addictive substance use impairs cognitive flexibility, with unclear underlying mechanisms. The reinforcement of substance use is mediated by the striatal direct-pathway medium spiny neurons (dMSNs) that projec...

    Himanshu Gangal, Xueyi **e, Zhenbo Huang, Yifeng Cheng… in Nature Communications (2023)

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