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  1. Article

    Open Access

    The Japanese Lung Cancer Society Guideline for non-small cell lung cancer, stage IV

    According to rapid development of chemotherapy in advanced non-small cell lung cancer (NSCLC), the Japan Lung Cancer Society has been updated its own guideline annually since 2010. In this latest version, all ...

    Hiroaki Akamatsu, Kiichiro Ninomiya in International Journal of Clinical Oncology (2019)

  2. No Access

    Article

    Combined antitumor effect of γ-secretase inhibitor and ABT-737 in Notch-expressing non-small cell lung cancer

    Inhibition of Notch by γ-secretase inhibitor (GSI) has been shown to have an antitumor effect in Notch-expressing non-small cell lung cancer (NSCLC) and to induce apoptosis through modulation of Bcl-2 family p...

    Jun Sakakibara-Konishi, Yasuyuki Ikezawa in International Journal of Clinical Oncology (2017)

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    Article

    Inhibition of Notch and HIF enhances the antitumor effect of radiation in Notch expressing lung cancer

    The Notch receptor plays an important role in various cell fate decisions during development and in cancer. We have previously reported that Notch3 is upregulated by radiation in non-small cell lung cancer (NS...

    Yasuyuki Ikezawa, Jun Sakakibara-Konishi in International Journal of Clinical Oncology (2017)

  4. No Access

    Article

    CD133 expression: a potential prognostic marker for non-small cell lung cancers

    CD133 is a membrane glycoprotein containing five transmembrane loops. Previous reports suggest that a CD133-positive subpopulation of multipotent cells with extensive proliferative and self-renewal characteris...

    Hidenori Mizugaki, Jun Sakakibara-Konishi in International Journal of Clinical Oncology (2014)