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  1. Article

    Open Access

    Non-invasive diagnosis of esophageal cancer by a simplified circulating cell-free DNA methylation assay targeting OTOP2 and KCNA3: a double-blinded, multicenter, prospective study

    Esophageal cancer (EC) is a highly lethal disease lacking early detection approaches. We previously identified that OTOP2 and KCNA3 were specifically hypermethylated in circulating cell-free DNA from patients ...

    Yan Bian, Ye Gao, Han Lin, Chang Sun, Wei Wang in Journal of Hematology & Oncology (2024)

  2. Article

    Open Access

    Neoadjuvant camrelizumab (an anti-PD-1 antibody) plus chemotherapy or apatinib (a VEGFR-2 inhibitor) for initially unresectable stage II–III non-small-cell lung cancer: a multicentre, two-arm, phase 2 exploratory study

    This multicentre, two-arm, phase 2 study aimed to explore the efficacy and safety of neoadjuvant camrelizumab plus chemotherapy or apatinib in patients with initially unresectable stage II–III non-small-cell l...

    Haoran **a, Han Zhang, Zheng Ruan in Signal Transduction and Targeted Therapy (2024)

  3. Article

    Correction to: The predictive value of inflammatory biomarkers for major pathological response in non-small cell lung cancer patients receiving neoadjuvant chemoimmunotherapy and its association with the immune-related tumor microenvironment: a multi-center study

    Chongwu Li, Junqi Wu, Long Jiang, Lei Zhang, Jia Huang in Cancer Immunology, Immunotherapy (2023)

  4. No Access

    Article

    The predictive value of inflammatory biomarkers for major pathological response in non-small cell lung cancer patients receiving neoadjuvant chemoimmunotherapy and its association with the immune-related tumor microenvironment: a multi-center study

    Inflammatory biomarkers in the peripheral blood have been established as predictors for immunotherapeutic efficacy in advanced non-small cell lung cancer (NSCLC). Whether they can also predict major pathologic...

    Chongwu Li, Junqi Wu, Long Jiang, Lei Zhang, Jia Huang in Cancer Immunology, Immunotherapy (2023)

  5. Article

    Open Access

    Esophagectomy versus definitive chemoradiotherapy for patients with clinical stage N0 and pathological stage T1b esophageal squamous cell carcinoma after endoscopic submucosal dissection: study protocol for a multicenter randomized controlled trial (Ad-ESD Trial)

    Esophagectomy is still advised as an additional treatment for pathological T1b (pT1b) esophageal squamous cell carcinoma (ESCC) following attempted endoscopic resection (ER). ER followed with definitive chemor...

    Yang Yang, Yuchen Su, **aobin Zhang, Jun Liu, Hong Zhang, Bin Li, Rong Hua in Trials (2020)

  6. Article

    Open Access

    Removal of tumor thrombus from the azygos vein in an esophageal squamous cell carcinoma patient

    Esophageal squamous cell carcinoma with tumor thrombus in the arch of the azygos vein has not been reported to date. Neoadjuvant chemotherapy can decrease the stage in patients with advanced preoperative tumor...

    Qijue Lu, Bowen Shi, Jiang Hong, Hezhong Chen in Journal of Cardiothoracic Surgery (2020)

  7. Article

    Open Access

    Combined use of gastric pull-up and pectoralis major flaps for massive defects after total laryngopharyngoesophagectomy in patients with advanced hypopharyngeal carcinoma

    Reconstruction for patients with advanced squamous cell carcinoma of the hypopharynx (SCCHP) after radical surgery is a challenge for head and neck surgeons, especially when one flap alone cannot entirely cove...

    Caiyun Zhang, Shicai Chen, Minhui Zhu in European Archives of Oto-Rhino-Laryngology (2015)