69 Result(s)
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Article
Coupled changes between ruminating thoughts and resting-state brain networks during the transition into adulthood
Perseverative negative thoughts, known as rumination, might arise from emotional challenges and preclude mental health when transitioning into adulthood. Due to its multifaceted nature, rumination can take sev...
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Open AccessLight Cannabis Use and the Adolescent Brain: An 8-years Longitudinal Assessment of Mental Health, Cognition, and Reward Processing
For decades, cannabis has been the most widely used illicit substance in the world, particularly among youth. Research suggests that mental health problems associated with cannabis use may result from its effe...
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Article
Open AccessIdentifying subgroups with differential response to CBASP versus Escitalopram during the first eight weeks of treatment in outpatients with persistent depressive disorder
There exists little empirical evidence hel** clinicians to select the most effective treatment for individual patients with persistent depressive disorder (PDD). This study identifies and characterizes subgr...
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Article
Open AccessPredictors of adherence to exercise interventions in people with schizophrenia
Exercise interventions are nowadays considered as effective add-on treatments in people with schizophrenia but are usually associated with high dropout rates. Therefore, the present study investigated potentia...
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Open AccessSmaller total and subregional cerebellar volumes in posttraumatic stress disorder: a mega-analysis by the ENIGMA-PGC PTSD workgroup
Although the cerebellum contributes to higher-order cognitive and emotional functions relevant to posttraumatic stress disorder (PTSD), prior research on cerebellar volume in PTSD is scant, particularly when c...
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Examining the association between posttraumatic stress disorder and disruptions in cortical networks identified using data-driven methods
Posttraumatic stress disorder (PTSD) is associated with lower cortical thickness (CT) in prefrontal, cingulate, and insular cortices in diverse trauma-affected samples. However, some studies have failed to det...
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Article
Correction: Arc controls alcohol cue relapse by a central amygdala mechanism
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Article
Differential associations of adolescent versus young adult cannabis initiation with longitudinal brain change and behavior
Leveraging ~10 years of prospective longitudinal data on 704 participants, we examined the effects of adolescent versus young adult cannabis initiation on MRI-assessed cortical thickness development and behavi...
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Article
Covariation of preadult environmental exposures, adult brain imaging phenotypes, and adult personality traits
Exposure to preadult environmental exposures may have long-lasting effects on mental health by affecting the maturation of the brain and personality, two traits that interact throughout the developmental proce...
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Open AccessHypothalamic volume in pedophilia with or without child sexual offense
The hypothalamus regulates sexual behavior and is simultaneously associated with aggression and violence. Consequently, this brain region is relevant in research of pedophilia and child sexual offenses (CSO). ...
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Article
Open AccessFunctional connectivity signatures of major depressive disorder: machine learning analysis of two multicenter neuroimaging studies
The promise of machine learning has fueled the hope for develo** diagnostic tools for psychiatry. Initial studies showed high accuracy for the identification of major depressive disorder (MDD) with resting-s...
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Article
Arc controls alcohol cue relapse by a central amygdala mechanism
Alcohol use disorder (AUD) is a chronic and fatal disease. The main impediment of the AUD therapy is a high probability of relapse to alcohol abuse even after prolonged abstinence. The molecular mechanisms of ...
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Article
Open AccessAnxiety onset in adolescents: a machine-learning prediction
Recent longitudinal studies in youth have reported MRI correlates of prospective anxiety symptoms during adolescence, a vulnerable period for the onset of anxiety disorders. However, their predictive value has...
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Cortical profiles of numerous psychiatric disorders and normal development share a common pattern
The neurobiological bases of the association between development and psychopathology remain poorly understood. Here, we identify a shared spatial pattern of cortical thickness (CT) in normative development and...
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Open AccessBehavioural and functional evidence revealing the role of RBFOX1 variation in multiple psychiatric disorders and traits
Common variation in the gene encoding the neuron-specific RNA splicing factor RNA Binding Fox-1 Homolog 1 (RBFOX1) has been identified as a risk factor for several psychiatric conditions, and rare genetic variant...
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Article
A causal association of ANKRD37 with human hippocampal volume
Human hippocampal volume has been separately associated with single nucleotide polymorphisms (SNPs), DNA methylation and gene expression, but their causal relationships remain largely unknown. Here, we aimed a...
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Open AccessBayesian causal network modeling suggests adolescent cannabis use accelerates prefrontal cortical thinning
While there is substantial evidence that cannabis use is associated with differences in human brain development, most of this evidence is correlational in nature. Bayesian causal network (BCN) modeling attempt...
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Open AccessIntact neural and behavioral correlates of emotion processing and regulation in weight-recovered anorexia nervosa: a combined fMRI and EMA study
Altered emotion processing and regulation mechanisms play a key role in eating disorders. We recently reported increased fMRI responses in brain regions involved in emotion processing (amygdala, dorsolateral p...
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Open AccessCorrection: Brain structural abnormalities in obesity: relation to age, genetic risk, and common psychiatric disorders
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Article
Open AccessAltered resting-state functional connectome in major depressive disorder: a mega-analysis from the PsyMRI consortium
Major depressive disorder (MDD) is associated with abnormal neural circuitry. It can be measured by assessing functional connectivity (FC) at resting-state functional MRI, that may help identifying neural mark...
