1 Result(s)

Article

Simple and cost-effective liquid chromatography-mass spectrometry method to measure dabrafenib quantitatively and six metabolites semi-quantitatively in human plasma

Dabrafenib is an inhibitor of BRAF V600E used for treating metastatic melanoma but a majority of patients experience adverse effects. Methods to measure the levels of dabrafenib and major metabolites during tr...

Svante Vikingsson, Jan-Olof Dahlberg… in Analytical and Bioanalytical Chemistry (2017)