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Article
Open AccessEndothelial specific prolyl hydroxylase domain-containing protein 2 deficiency attenuates aging-related obesity and exercise intolerance
Obesity and exercise intolerance greatly reduce the life quality of older people. Prolyl hydroxylase domain-containing protein 2 (PHD2) is an important enzyme in modulating hypoxia-inducible factor-alpha (HIF)...
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Article
Open AccessGLP-1 receptor agonists’ impact on cardio-renal outcomes and mortality in T2D with acute kidney disease
Previous studies have explored the effects of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) in reducing cardiovascular events in type 2 diabetes. Here we show that GLP-1 RAs are associated with lower r...
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Article
Open AccessMeasurement of e+e− → ωη′ cross sections at \( \sqrt{s} \) = 2.000 to 3.080 GeV
We measured the Born cross sections for the process e+e− → ωη′ at 22 center-of-mass energies from 2.000 to 3.080 GeV with the BESIII detector at the BEPCII collider. We observed a resonant structure with a statis...
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Article
Evaluation of pancreatic iodine uptake and related influential factors in multiphase dual-energy CT
To establish normative values and identify potential factors influencing pancreatic iodine uptake using dual-energy CT (DECT).
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Article
Open AccessStructural basis for recognition of 26RFa by the pyroglutamylated RFamide peptide receptor
The neuropeptide 26RFa, a member of the RF-amide peptide family, activates the pyroglutamylated RF-amide peptide receptor (QRFPR), a class A GPCR. The 26RFa/QRFPR system plays critical roles in energy homeosta...
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Article
Dimerization and antidepressant recognition at noradrenaline transporter
The noradrenaline transporter has a pivotal role in regulating neurotransmitter balance and is crucial for normal physiology and neurobiology1. Dysfunction of noradrenaline transporter has been implicated in nume...
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Article
Open AccessMeasurement of absolute branching fractions of \( {\textrm{D}}_{\textrm{s}}^{+} \) hadronic decays
Using e+e− collision data collected at the BESIII detector at center-of-mass energies between 4.128 and 4.226 GeV, corresponding to an integrated luminosity of 7.33 fb−1, we determine the absolute branching fract...
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Article
Open AccessSearch for ∆S = 2 nonleptonic hyperon decays Ω− → Σ0π− and Ω− → nK−
Using (27.12 ± 0.14) × 108 ψ(3686) events collected by the BESIII detector at the center-of-mass energy of ...
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Article
Open AccessMeasurement of Born cross section of \( {e}^{+}{e}^{-}\to {\Sigma}^{+}{\overline{\Sigma}}^{-} \) at center-of-mass energies between 3.510 and 4.951 GeV
Using 24.1 fb−1 of e+e− collision data collected with the BESIII detector at the BEPCII collider, the Born cross sections and effective form factors of the ...
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Article
Open AccessUrinary volatile organic compound metabolites and COPD among US adults: mixture, interaction and mediation analysis
Volatile organic compounds (VOCs) encompass hundreds of high production volume chemicals and have been reported to be associated with adverse respiratory outcomes such as chronic obstructive pulmonary disease ...
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Article
Two New Antibacterial Isoindolin-1-Ones from Sun-Cured Tobacco and Their Potential Application in Antiseptic Cigarette Tip** Paper
Two new isoindolin-1-ones (1 and 2), were isolated from the stems of Nicotiana tabacum (a cultivar of sun-cured tobacco with high resistance to black shank diseases, which originated from Huize local sun-cured to...
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Article
Multimorbidity patterns and health-related quality of life among community-dwelling older adults: evidence from a rural town in Suzhou, China
The high prevalence of multimorbidity in aging societies has posed tremendous challenges to the healthcare system. The aim of our study was to comprehensively assess the association of multimorbidity patterns ...
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Article
Open AccessA secure and highly efficient blockchain PBFT consensus algorithm for microgrid power trading
There are a series of challenges in microgrid transactions, and blockchain technology holds the promise of addressing these challenges. However, with the increasing number of users in microgrid transactions, e...
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Article
Open AccessCRL4DCAF13 E3 ubiquitin ligase targets MeCP2 for degradation to prevent DNA hypermethylation and ensure normal transcription in growing oocytes
The DNA methylation is gradually acquired during oogenesis, a process sustained by successful follicle development. However, the functional roles of methyl-CpG-binding protein 2 (MeCP2), an epigenetic regulato...
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Article
Thermodynamic and Economic Analysis of a Conceptual System Combining Sludge Gasification, SOFC, Supercritical CO2 Cycle, and Organic Rankine Cycle
In order to reduce the environmental impact of conventional sludge treatment methods and to utilize the energy in sludge more effectively, a coupled system based on sewage sludge gasifier (SSG), solid oxide fu...
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Article
Open AccessObservation of ψ(3686) → \( {\varOmega}^{-}{K}^{+}{\overline{\**}}^0 \) + c.c.
Using (27.12 ± 0.14) × 108 ψ(3686) events collected with the BESIII detector at BEPCII, the decay of ψ(3686) → ...
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Article
Open AccessThe role of wearable home blood pressure monitoring in detecting out-of-office control status
Ambulatory blood pressure (ABP) and home blood pressure (HBP) monitoring is currently recommended for management of hypertension. Nonetheless, traditional HBP protocols could overlook diurnal fluctuations, whi...
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Article
Open AccessTranscriptomic changes in the microsporidia proliferation and host responses in congenitally infected embryos and larvae
Congenital infection caused by vertical transmission of microsporidia N. bombycis can result in severe economic losses in the silkworm-rearing industry. Whole-transcriptome analyses have revealed non-coding RNAs ...
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Article
CO emission predictions in municipal solid waste incineration based on reduced depth features and long short-term memory optimization
Carbon monoxide (CO) is a toxic gas emitted during municipal solid waste incineration (MSWI). Its emission prediction is conducive to pollutant reduction and optimized control of MSWI. The variables of MSWI ex...
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Article
Open AccessCarbapenem-resistant Klebsiella pneumoniae capsular types, antibiotic resistance and virulence factors in China: a longitudinal, multi-centre study
Epidemiological knowledge of circulating carbapenem-resistant Klebsiella pneumoniae (CRKP) is needed to develop effective strategies against this public health threat. Here we present a longitudinal analysis of 1...
