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  1. Article

    Open Access

    Combination of pan-RAF and MEK inhibitors in NRAS mutant melanoma

    Approximately 20% of melanomas contain a mutation in NRAS. However no direct inhibitor of NRAS is available. One of the main signaling pathways downstream of NRAS is the MAPK pathway. In this study we investig...

    Mohammad Atefi, Bjoern Titz, Earl Avramis, Charles Ng, Deborah JL Wong… in Molecular Cancer (2015)

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