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  1. Article

    Open Access

    Relation Between Endothelial Dysfunction and Exercise Training-Mediated Adaptation in Cardiovascular Risk Factors, Cardiorespiratory Fitness, and Vascular Health in Humans: A secondary analysis

    A priori cardiovascular (CV) health status may impact reductions in risk factors and CV mortality and morbidity following exercise training, although this is not fully understood. Therefore, the purpose of the...

    Hannah L. McLellan, Ellen A. Dawson in Journal of Science in Sport and Exercise (2024)

  2. Article

    Open Access

    The impact of age, sex, cardio-respiratory fitness, and cardiovascular disease risk on dynamic cerebral autoregulation and baroreflex sensitivity

    Humans display an age-related decline in cerebral blood flow and increase in blood pressure (BP), but changes in the underlying control mechanisms across the lifespan are less well understood. We aimed to; (1)...

    Joseph D. Maxwell, Daniel J. Bannell in European Journal of Applied Physiology (2022)

  3. Article

    Open Access

    Cocoa-flavanols enhance moderate-intensity pulmonary \(\dot{V}{\text{O}}_{2}\) kinetics but not exercise tolerance in sedentary middle-aged adults

    Cocoa flavanols (CF) may exert health benefits through their potent vasodilatory effects, which are perpetuated by elevations in nitric oxide (NO) bioavailability. These vasodilatory effects may contribute to ...

    Daniel G. Sadler, Richard Draijer in European Journal of Applied Physiology (2021)

  4. Article

    Open Access

    Can exercise training enhance the repeated remote ischaemic preconditioning stimulus on peripheral and cerebrovascular function in high-risk individuals?

    Repeated exposure to remote ischaemic preconditioning (rIPC; short bouts of non-lethal ischaemia) enhances peripheral vascular function within 1 week; whereas, longer periods of rIPC (~ 1 year) may improve cer...

    Joseph D. Maxwell, Madeleine France in European Journal of Applied Physiology (2021)

  5. Article

    Open Access

    Postexercise hypotension and related hemodynamic responses to cycling under heat stress in untrained men with elevated blood pressure

    To investigate the effect of heat stress on postexercise hypotension.

    Felipe A. Cunha, Paulo Farinatti, Helen Jones in European Journal of Applied Physiology (2020)

  6. Article

    Open Access

    The impact of acute remote ischaemic preconditioning on cerebrovascular function

    Remote ischaemic preconditioning (RIPC) refers to the protection conferred to tissues and organs via brief periods of ischaemia in a remote vascular territory, including the brain. Recent studies in humans rep...

    Howard H. Carter, Joseph D. Maxwell in European Journal of Applied Physiology (2020)

  7. Article

    Open Access

    High-intensity exercise in the evening does not disrupt sleep in endurance runners

    To investigate the effect of early evening exercise training at different intensities on nocturnal sleep and cardiac autonomic activity in endurance-trained runners.

    Craig Thomas, Helen Jones, Craig Whitworth-Turner in European Journal of Applied Physiology (2020)

  8. Article

    Open Access

    Historical reviews of the assessment of human cardiovascular function: interrogation and understanding of the control of skin blood flow

    Several techniques exist for the determination of skin blood flow that have historically been used in the investigation of thermoregulatory control of skin blood flow, and more recently, in clinical assessment...

    David. A. Low, Helen Jones, N. Tim Cable in European Journal of Applied Physiology (2020)

  9. Article

    Open Access

    The effect of local repeated passive heating and handgrip exercise on reflex cutaneous vascular and sudomotor responses to whole-body heat stress

    David A Low, Thomas G Bailey, Danielle Turner in Extreme Physiology & Medicine (2015)

  10. No Access

    Article

    The right ventricle following ultra-endurance exercise: insights from novel echocardiography and 12-lead electrocardiography

    There is contradictory evidence related to the impact of ultra-marathon running on right ventricular (RV) structure and function. Consequently, the aims of this study were to: (1) comprehensively assess RV str...

    Rachel Lord, John Somauroo, Mike Stembridge in European Journal of Applied Physiology (2015)

  11. No Access

    Article

    Effects of dawn simulation on markers of sleep inertia and post-waking performance in humans

    To examine the effects of a simulated dawn during the last 30 min of sleep on the subsequent dissipation of sleep inertia and changes in simulated work and physical performance.

    Andrew Thompson, Helen Jones, Warren Gregson in European Journal of Applied Physiology (2014)

  12. No Access

    Article

    Blood pressure regulation VII. The “morning surge” in blood pressure: measurement issues and clinical significance

    In kee** with this review-series theme, we question whether the morning surge in blood pressure (MSBP) is a benign response to the physiological challenges during the first 3 h after waking, or is it clinica...

    Greg Atkinson, Alan M. Batterham, Kazuomi Kario in European Journal of Applied Physiology (2014)

  13. No Access

    Article

    Circadian variation in the circulatory responses to exercise: relevance to the morning peaks in strokes and cardiac events

    Sudden cardiac and cerebral events are most common in the morning. A fundamental question is whether these events are triggered by the increase in physical activity after waking, and/or a result of circadian v...

    Greg Atkinson, Helen Jones, Philip N. Ainslie in European Journal of Applied Physiology (2010)

  14. No Access

    Article

    The acute post-exercise response of blood pressure varies with time of day

    The reactivity of ambulatory blood pressure following a given change in everyday physical activities is highest in the morning. Whether the acute response of blood pressure following a controlled bout of steady-s...

    Helen Jones, Christopher Pritchard, Keith George in European Journal of Applied Physiology (2008)

  15. No Access

    Article

    Is the magnitude of acute post-exercise hypotension mediated by exercise intensity or total work done?

    The purpose of this study was to investigate the effects of exercise intensity on the magnitude of acute post-exercise hypotension while controlling for total work done over the exercise bout. Seven normotensi...

    Helen Jones, Keith George, Ben Edwards in European Journal of Applied Physiology (2007)