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  1. Article

    Open Access

    Integrated analysis of microbiome and host transcriptome reveals correlations between gut microbiota and clinical outcomes in HBV-related hepatocellular carcinoma

    The gut-liver axis plays a pivotal role in the pathogenesis of hepatocellular carcinoma (HCC). However, the correlations between the gut microbiome and the liver tumor transcriptome in patients with HCC and th...

    Hechen Huang, Zhigang Ren, **ngxing Gao, **aoyi Hu, Yuan Zhou in Genome Medicine (2020)

  2. Article

    Open Access

    HJURP promotes hepatocellular carcinoma proliferation by destabilizing p21 via the MAPK/ERK1/2 and AKT/GSK3β signaling pathways

    Holliday junction recognition protein (HJURP) has been implicated in many cancers including hepatocellular carcinoma (HCC). However, the underlying mechanism by which HJURP promotes HCC cell proliferation rema...

    Tianchi Chen, Hechen Huang, Yuan Zhou in Journal of Experimental & Clinical Cancer … (2018)