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Article
Open AccessRefining silicon nitride waveguide quality through femtosecond laser annealing
We present a method for modification of silicon nitride (Si3N4) waveguide resonators using femtosecond laser annealing. The quality (Q) factor of the waveguide resonators can be improved by approximately 1.3 time...
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Article
Open AccessFedSHE: privacy preserving and efficient federated learning with adaptive segmented CKKS homomorphic encryption
Unprotected gradient exchange in federated learning (FL) systems may lead to gradient leakage-related attacks. CKKS is a promising approximate homomorphic encryption scheme to protect gradients, owing to its u...
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Article
Open AccessSlit2–Robo4 signal pathway and tight junction in intestine mediate LPS-induced inflammation in mice
Sepsis is one of the most common clinical diseases, which is characterized by a serious and uncontrollable inflammatory response. LPS-induced inflammation is a critical pathological event in sepsis, but the un...
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Article
Open AccessDe novo design of a nanoregulator for the dynamic restoration of ovarian tissue in cryopreservation and transplantation
The cryopreservation and transplantation of ovarian tissue underscore its paramount importance in safeguarding reproductive capacity and ameliorating reproductive disorders. However, challenges persist in ovar...
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Article
Experimental quantum computational chemistry with optimized unitary coupled cluster ansatz
Quantum computational chemistry has emerged as a potential application of quantum computing. Hybrid quantum-classical computing methods, such as variational quantum eigensolvers, have been designed as promisin...
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Article
Opportunities and challenges of high-entropy materials in lithium-ion batteries
Lithium-ion batteries (LIBs) currently occupy an important position in the energy storage market, and the development of advanced LIBs with higher energy density and power density, better cycle life and safety...
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Article
Open AccessCu(II)-based complex loaded with drug paclitaxel hydrogels against thyroid cancer and optimizing novel derivatives
This study introduces a novel approach for synthesizing a Cu(II)-based coordination polymer (CP), {[Cu(L)(4,4´-OBA)]·H2O}n (1), using a mixed ligand method. The CP was successfully prepared by reacting Cu(NO3)2·3...
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Article
Open AccessCreatine and l-carnitine attenuate muscular laminopathy in the LMNA mutation transgenic zebrafish
Lamin A/C gene (LMNA) mutations contribute to severe striated muscle laminopathies, affecting cardiac and skeletal muscles, with limited treatment options. In this study, we delve into the investigations of five ...
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Article
Open AccessYAP promotes the early development of temporomandibular joint bony ankylosis by regulating mesenchymal stem cell function
To explore the role of YAP, a key effector of the Hippo pathway, in temporomandibular joint (TMJ) ankylosis. The temporal and spatial expression of YAP was detected via immunohistochemistry and multiplex immun...
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Article
Down-regulation of RTEL1 Improves M1/M2 Macrophage Polarization by Promoting SFRP2 in Fibroblasts-derived Exosomes to Alleviate COPD
Chronic obstructive pulmonary disease (COPD) is a common chronic respiratory disease worldwide. Macrophage polarization plays a substantial role in the pathogenesis of COPD. This study is aimed to explore the ...
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Article
Open AccessAgrin-Lrp4 pathway in hippocampal astrocytes restrains development of temporal lobe epilepsy through adenosine signaling
Human patients often experience an episode of serious seizure activity, such as status epilepticus (SE), prior to the onset of temporal lobe epilepsy (TLE), suggesting that SE can trigger the development of ep...
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Article
Open AccessBoson star superradiance
Recently, it has been realized that in some systems internal space rotation can induce energy amplification for scattered waves, similar to rotation in real space. In particularly, it has been shown that energ...
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Article
Open AccessRevealing the pharmacological mechanisms of nao-an drop** pill in preventing and treating ischemic stroke via the PI3K/Akt/eNOS and Nrf2/HO-1 pathways
Nao-an Drop** Pill (NADP) is a Chinese patent medicine which commonly used in clinic for ischemic stroke (IS). However, the material basis and mechanism of its prevention or treatment of IS are unclear, then...
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Article
Open AccessRole of umbilical cord mesenchymal stromal cells in skin rejuvenation
Aging is the main cause of many degenerative diseases. The skin is the largest and the most intuitive organ that reflects the aging of the body. Under the interaction of endogenous and exogenous factors, there...
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Article
Technical variety of anastomotic techniques used in proximal gastrectomy with double-tract-reconstruction - a narrative review
In the past 40 years, the incidence of esophagogastric junction cancer has been gradually increasing worldwide. Currently, surgical resection remains the main radical treatment for early gastric cancer. Due to...
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Article
Open AccessRisk factors for renal outcomes in children with antineutrophil cytoplasmic antibody-associated vasculitis: a nationwide retrospective study in China
Pediatric antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is a life-threatening systemic vasculitis featured by liability to renal involvement. However, there are few studies on the risk factor...
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Article
Open AccessDiet and lifestyle behaviours simultaneously act on frailty: it is time to move the threshold of frailty prevention and control forward
To analyse the association among the simultaneous effects of dietary intake, daily life behavioural factors, and frailty outcomes in older Chinese women, we predicted the probability of maintaining physical ro...
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Article
Study on the flow structure in curved open channels with suspended vegetation using multi relaxation time lattice Boltzmann method
Suspended vegetation in rivers, lakes, reservoirs and canals can change flow structure, which will in turn affect the sediment transport and cause the variation of water ecological environment. In order to stu...
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Article
RuCo alloy nanoparticles embedded within N-doped porous two-dimensional carbon nanosheets: a high-performance hydrogen evolution reaction catalyst
Develo** cost-effective electrocatalysts with high activity and stability especially at high current density is of great significance for the large-scale commercial application of electrochemical water split...
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Article
Nonsingular Fast Terminal Sliding Mode Control Strategy for PMLSM Based on Disturbance Compensation
To optimize the anti-interference performance and dynamic response ability of permanent magnet linear synchronous motor (PMLSM) and enhance the overall control performance of the system, the novel nonsingular ...
