12 Result(s)
-
Article
Open AccessA systematic literature review of the key challenges for develo** the structure of public health economic models
To identify the key methodological challenges for public health economic modelling and set an agenda for future research.
-
Article
Trastuzumab Emtansine for Treating HER2-Positive, Unresectable, Locally Advanced or Metastatic Breast Cancer After Treatment with Trastuzumab and a Taxane: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
The National Institute for Health and Care Excellence (NICE) invited the manufacturer of trastuzumab emtansine (T-DM1) (Kadcyla®; Roche) to submit evidence of its clinical and cost-effectiveness for treating huma...
-
Article
Pertuzumab for the Neoadjuvant Treatment of Early-Stage HER2-Positive Breast Cancer: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
As part of its single technology appraisal process, the National Institute for Health and Care Excellence invited the manufacturer of pertuzumab (Perjeta®; Roche Products Limited) to submit evidence of its clinic...
-
Article
Pembrolizumab for Locally Advanced or Metastatic Urothelial Cancer Where Cisplatin is Unsuitable: An Evidence Review Group Perspective of a NICE Single Technology Appraisal
As part of its Single Technology Appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer (Merck Sharp & Dohme) of pembrolizumab (Keytruda®) to submit evidenc...
-
Article
Open AccessConceptualising changes to tobacco and alcohol policy as affecting a single interlinked system
To support a move towards a coordinated non-communicable disease approach in public health policy, it is important to conceptualise changes to policy on tobacco and alcohol as affecting a single interlinked sy...
-
Article
Open AccessQualitative research to inform economic modelling: a case study in older people’s views on implementing the NICE falls prevention guideline
High prevalence of falls among older persons makes falls prevention a public health priority. Yet community-based falls prevention face complexity in implementation and any commissioning strategy should be sub...
-
Article
Open AccessEconomic models of community-based falls prevention: a systematic review with subsequent commissioning and methodological recommendations
Falls impose significant health and economic burdens among older populations, making their prevention a priority. Health economic models can inform whether the falls prevention intervention represents a cost-e...
-
Article
Open AccessEconomic evaluation of community-based falls prevention interventions for older populations: a systematic methodological overview of systematic reviews
Falls impose significant health and economic burdens on older people. The volume of falls prevention economic evaluations has increased, the findings from which have been synthesised by systematic reviews (SRs...
-
Article
Open AccessSystematic review and critical methodological appraisal of community-based falls prevention economic models
Falls impose significant health and economic burdens on community-dwelling older persons. Decision modelling can inform commissioning of alternative falls prevention strategies. Several methodological challeng...
-
Article
Open AccessEconomic model of community-based falls prevention: seeking methodological solutions in evaluating the efficiency and equity of UK guideline recommendations
Falls significantly harm geriatric health and impose substantial costs on care systems and wider society. Decision modelling can inform the commissioning of falls prevention but face methodological challenges,...
-
Article
Open AccessThe association between health-related quality of life and problem gambling severity: a cross-sectional analysis of the Health Survey for England
Problem gambling can lead to health-related harms, such as poor mental health and suicide. In the UK there is interest in introducing guidance around effective and cost-effective interventions to prevent harm ...
-
Article
Open AccessIncorporating frailty to address the key challenges to geriatric economic evaluation
The multidimensional and dynamically complex process of ageing presents key challenges to economic evaluation of geriatric interventions, including: (1) accounting for indirect, long-term effects of a geriatri...
