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  1. Article

    Open Access

    Safety and Antitumor Activity of Repeated ASP3026 Administration in Japanese Patients with Solid Tumors: A Phase I Study

    Anaplastic lymphoma kinase gene rearrangements (ALKr) resulting in EML4–ALK proteins occur in a subset of solid tumors and are targeted by ALK inhibitors. Given the development of drug resistance to ALK inhibitor...

    Akira Ono, Haruyasu Murakami, Takashi Seto, Toshio Shimizu, Sawori Watanabe in Drugs in R&D (2021)