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Article
Immunohistochemical analysis of transporters related to clearance of amyloid-β peptides through blood–cerebrospinal fluid barrier in human brain
A large number of previous reports have focused on the transport of amyloid-β peptides through cerebral endothelial cells via the blood–brain barrier, while fewer reports have mentioned the transport through t...
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Chapter
Pediatric Medullomyoblastoma: Immunohistochemical Analyses
Medullomyoblastoma is a rare embryonal tumor of the central nervous system and is classified as medulloblastoma with myogenic differentiation according to the most recent WHO classification, 4th edition. The t...
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Article
Axonal damage in acute cerebral infarction showing ADC reduction
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Article
The expression of LDL receptor in vessels with blood–brain barrier impairment in a stroke-prone hypertensive model
We previously reported that the blood–brain barrier (BBB) function was deteriorated in vessels located in the hippocampus in stroke-prone spontaneously hypertensive rats (SHRSP). In order to assess whether sub...
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Article
The expression of matrix metalloproteinase-13 is increased in vessels with blood–brain barrier impairment in a stroke-prone hypertensive model
We previously reported that the blood–brain barrier (BBB) function was deteriorated in vessels located in the hippocampus, but not the cerebral cortex, in 3-month-old stroke-prone spontaneously hypertensive ra...
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Article
Two pathways of apoptosis are simultaneously induced in the embryonal brains of neural cell-specific HIF-1α-deficient mice
The aim of this study was to clarify the mechanism of apoptosis seen in the cortex of neural cell-specific hypoxia inducible factor-1α (HIF-1α)-deficient embryos. A previous study showed that the neural cells ...
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Article
Blood-brain barrier disruption in the hypothalamus of young adult spontaneously hypertensive rats
Vascular permeability and endothelial glycocalyx were examined in young adult spontaneously hypertensive rats (SHR), stroke-prone SHR (SHRSP), and Wistar Kyoto rats (WKY) as a control, in order to determine ea...
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Article
Blood-brain barrier is impaired in the hippocampus of young adult spontaneously hypertensive rats
A causative role of blood-brain barrier (BBB) impairment is suggested in the pathogenesis of vascular dementia with leakage of serum components from small vessels leading to neuronal and glial damage. We exami...
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Article
Ultrastructural and permeability features of microvessels in the olfactory bulbs of SAM mice
The ultrastructural features of microvessels showing increased permeability to intravenously injected horseradish peroxidase (HRP) were examined in the olfactory bulbs of senescence-accelerated prone mice (SA...
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Article
Age-related changes in the brain transfer of blood-borne horseradish peroxidase in the hippocampus of senescence-accelerated mouse
Age-related changes in the brain transfer of blood-borne horseradish peroxidase (HRP) were examined by light microscopy in senescence-accelerated prone mice (SAMP8) and senescence-accelerated resistant mice (...
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Article
An ultrastructural study of malignant fibrous histiocytoma of the larynx
Malignant fibrous histiocytoma (MFH) of the vocal cord occurring in a 46-year-old male was studied immunohistochemically and ultrastructurally. The tumor consisted of the two main areas, pleomorphic and storif...
