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Article
Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolution using T2C
This protocol describes targeted chromatin capture (T2C), a high-resolution method to interrogate 3D chromatin organization and genomic interactions at sub-kilobase-pair resolution that requires minimal cell n...
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Article
Robust 4C-seq data analysis to screen for regulatory DNA interactions
A high-resolution 4C-seq protocol involving two restriction digests and a revised analysis pipeline allows robust detection of physical interactions between regulatory DNA elements.