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within Harmen J. G. van de Werken Remove this filter Life Sciences Remove this filter Biological Techniques Remove this filter

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  1. No Access

    Article

    Investigation of the spatial structure and interactions of the genome at sub-kilobase-pair resolution using T2C

    This protocol describes targeted chromatin capture (T2C), a high-resolution method to interrogate 3D chromatin organization and genomic interactions at sub-kilobase-pair resolution that requires minimal cell n...

    Petros Kolovos, Rutger W W Brouwer, Christel E M Kockx… in Nature Protocols (2018)

  2. No Access

    Article

    Robust 4C-seq data analysis to screen for regulatory DNA interactions

    A high-resolution 4C-seq protocol involving two restriction digests and a revised analysis pipeline allows robust detection of physical interactions between regulatory DNA elements.

    Harmen J G van de Werken, Gilad Landan, Sjoerd J B Holwerda… in Nature Methods (2012)