5 Result(s)
within
Hannah V Siddle
Biomedicine
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Article
Open AccessExploring the landscape of Babesia bovis vaccines: progress, challenges, and opportunities
Bovine babesiosis, caused by different Babesia spp. such as B. bovis, B. bigemina, B. divergens, and B. major, is a global disease that poses a serious threat to livestock production. Babesia bovis infections are...
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Article
Open AccessThe role of MHC genes in contagious cancer: the story of Tasmanian devils
The Tasmanian devil, a marsupial species endemic to the island of Tasmania, harbours two contagious cancers, Devil Facial Tumour 1 (DFT1) and Devil Facial Tumour 2 (DFT2). These cancers pass between individual...
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Article
High levels of genetic variation at MHC class II DBB loci in the tammar wallaby (Macropus eugenii)
High levels of MHC diversity are crucial for immunological fitness of populations, with island populations particularly susceptible to loss of genetic diversity. In this study, the level of MHC class II DBB di...
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Article
Characterization of major histocompatibility complex class I and class II genes from the Tasmanian devil (Sarcophilus harrisii)
The Tasmanian devil (Sarcophilus harrisii) is currently threatened by an emerging wildlife disease, devil facial tumour disease. The disease is decreasing devil numbers dramatically and may lead to the extinction...
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Article
Isolation of major histocompatibility complex Class I genes from the tammar wallaby (Macropus eugenii)
The major histocompatibility complex (MHC) plays an essential role in the adaptive immune system of vertebrates through antigen recognition. Although MHC genes are found in all vertebrates, the MHC region is d...
