76 Result(s)
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Han** Zhao
Science, Humanities and Social Sciences, multidisciplinary
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Article
Open AccessHuman neutralizing antibodies target a conserved lateral patch on H7N9 hemagglutinin head
Avian influenza A virus H7N9 causes severe human infections with >30% fatality. Currently, there is no H7N9-specific prevention or treatment for humans. Here, from a 2013 H7N9 convalescent case in Hong Kong, w...
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Open AccessExperiments as Code and its application to VR studies in human-building interaction
Experiments as Code (ExaC) is a concept for reproducible, auditable, debuggable, reusable, & scalable experiments. Experiments are a crucial tool to understand Human-Building Interactions (HBI) and build a coh...
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Open AccessEffects of different temperatures on Leiocassis longirostris gill structure and intestinal microbial composition
Fish are poikilothermic vertebrates and their physiological activities are affected by water temperature. In recent years, extreme weather has occurred frequently, and temperature changes have adversely affect...
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Open AccessDevelo** a machine learning model for accurate nucleoside hydrogels prediction based on descriptors
Supramolecular hydrogels derived from nucleosides have been gaining significant attention in the biomedical field due to their unique properties and excellent biocompatibility. However, a major challenge in th...
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Open AccessTemporally-coordinated bivalent histone modifications of BCG1 enable fungal invasion and immune evasion
Bivalent histone modifications, including functionally opposite H3K4me3 and H3K27me3 marks simultaneously on the same nucleosome, control various cellular processes by fine-tuning the gene expression in eukary...
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Open AccessNon-linear association between daily mean temperature and children’s hand foot and mouth disease in Chongqing, China
Chongqing was seriously affected by hand, foot, and mouth disease (HFMD), but the relationships between daily mean temperature and the incidence of HFMD remain unclear. This study used distributed lag nonlinea...
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Open AccessSimulation test study on filling flow law of gangue slurry in goaf
The disposal and utilization of solid waste of coal gangue is one of the main problems in coal mining in China. Injecting coal gangue into goaf in the form of slurry can effectively solve the problems of groun...
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Open AccessA high-quality chromosome-level wild rice genome of Oryza coarctata
Oryza coarctata (2n = 4X = 48, KKLL) is an allotetraploid, undomesticated relative of rice and the only species in the genus Oryza with tolerance to high salinity and submergence. Therefore, it contains important...
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Open AccessPreoperative albumin-to-globulin ratio and prognostic nutritional index predict the prognosis of colorectal cancer: a retrospective study
The immunonutritional status has important effects on outcomes for cancer patients. Albumin-to-globulin ratio (AGR) and the prognostic nutrition index (PNI) are often used to assess the immunonutritional statu...
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Open AccessEfficacy and safety of epigallocatechin-3-gallate in treatment acute severe dermatitis in patients with cancer receiving radiotherapy: a phase I clinical trial
To evaluate the safety and effectiveness of epigallocatechin-3-gallate (EGCG) solution treating the acute severe dermatitis in patients receiving radiotherapy. This phase I research enrolled patients with thor...
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Open AccessNovel treatment of chalazion using light-guided-tip intense pulsed light
We assessed the effectiveness of light-guided-tip intense pulsed light (IPL) with meibomian gland expression (MGX) in chalazion treatment. Ninety-five eyes with chalazion received a light-guided-tip IPL-MGX tr...
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Open AccessA Phytophthora receptor-like kinase regulates oospore development and can activate pattern-triggered plant immunity
Plant cell-surface leucine-rich repeat receptor-like kinases (LRR-RLKs) and receptor-like proteins (LRR-RLPs) form dynamic complexes to receive a variety of extracellular signals. LRR-RLKs are also widespread ...
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Open AccessTopological solitonic macromolecules
Being ubiquitous, solitons have particle-like properties, exhibiting behaviour often associated with atoms. Bound solitons emulate dynamics of molecules, though solitonic analogues of polymeric materials have ...
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Open AccessIn situ activation of flexible magnetoelectric membrane enhances bone defect repair
For bone defect repair under co-morbidity conditions, the use of biomaterials that can be non-invasively regulated is highly desirable to avoid further complications and to promote osteogenesis. However, it re...
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Open AccessBacteriophage targeting microbiota alleviates non-alcoholic fatty liver disease induced by high alcohol-producing Klebsiella pneumoniae
Our previous studies have shown that high alcohol-producing Klebsiella pneumoniae (HiAlc Kpn) in the intestinal microbiome could be one of the causes of non-alcoholic fatty liver disease (NAFLD). Considering anti...
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Open AccessIntegrated analysis of how gender and body weight affect the intestinal microbial diversity of Gymnocypris chilianensis
Intestinal microorganisms that living in the mucosa and contents of the gastrointestinal tract of animals, have close links with their hosts over a long evolutionary history. The community structure of the fis...
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Open AccessEnergy-efficient high-fidelity image reconstruction with memristor arrays for medical diagnosis
Medical imaging is an important tool for accurate medical diagnosis, while state-of-the-art image reconstruction algorithms raise critical challenges in massive data processing for high-speed and high-quality ...
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Open AccessLimitations of gene editing assessments in human preimplantation embryos
Range of DNA repair in response to double-strand breaks induced in human preimplantation embryos remains uncertain due to the complexity of analyzing single- or few-cell samples. Sequencing of such minute DNA ...
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Open AccessTHADA inhibition in mice protects against type 2 diabetes mellitus by improving pancreatic β-cell function and preserving β-cell mass
Impaired insulin secretion is a hallmark in type 2 diabetes mellitus (T2DM). THADA has been identified as a candidate gene for T2DM, but its role in glucose homeostasis remains elusive. Here we report that THADA ...
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A universal interface for plug-and-play assembly of stretchable devices
Stretchable hybrid devices have enabled high-fidelity implantable1–3 and on-skin4–6 monitoring of physiological signals. These devices typically contain soft modules that match the mechanical requirements in huma...
