24 Result(s)
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Haiyong **
Internal Medicine
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Article
Open AccessGiant cell tumor of soft tissue involving thyroid gland: a case report and review of the literature
Giant cell tumor of soft tissue is a low malignant uncommon neoplasm, with histologic features and immunophenotype similar to its bone counterpart. Primary giant cell tumor of soft tissue in the thyroid gland ...
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Correction: ROR1-targeting switchable CAR-T cells for cancer therapy
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Open AccessChanges in Site of Death Among Older Adults Without a COVID-19 Diagnosis During the COVID-19 Pandemic
Understanding how the coronavirus disease 2019 (COVID-19) pandemic affected site of death—an important patient-centered outcome related to end-of-life care—would inform healthcare system resiliency in future p...
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Open AccessDevelopment and clinical application of loop-mediated isothermal amplification combined with lateral flow assay for rapid diagnosis of SARS-CoV-2
The diagnostic assay leveraging multiple reverse transcription loop-mediated isothermal amplification (RT-LAMP) could meet the requirements for rapid nucleic acid detection of severe acute respiratory syndrome...
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Open AccessAntioxidative stress protein SRXN1 can be used as a radiotherapy prognostic marker for prostate cancer
To explore the mechanisms of radiotherapy resistance and search for prognostic biomarkers for prostate cancer.
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Open AccessEPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers
The aim of the study was to investigate predictive value of gene mutation for atezolizumab treatment response from OAK and POPLAR cohorts.
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ROR1-targeting switchable CAR-T cells for cancer therapy
The success of chimeric antigen receptor T cell (CAR-T) therapy in the treatment of hematologic malignancies has prompted the development of numerous CAR-T technologies, including switchable CAR-T (sCAR-T) sys...
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Open AccessSingle-cell sequencing reveals MYC targeting gene MAD2L1 is associated with prostate cancer bone metastasis tumor dormancy
Among malignant tumors, bone metastasis is frequently associated with prostate cancer which is seen in about 80% of patients. During cancer treatments, some tumor cells switch to a "dormant mode" to help tumor...
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Drug resistance of targeted therapy for advanced non-small cell lung cancer harbored EGFR mutation: from mechanism analysis to clinical strategy
Non-small cell lung cancer (NSCLC) accounts for about 85% in all cases of lung cancer. In recent years, molecular targeting drugs for NSCLC have been developed rapidly. The epidermal growth factor receptor-tyr...
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Open AccessTherapeutic utility of Lung-MAP: ushering into an era of genomic and biomarker-driven clinical trials
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Open AccessTreatment of posttraumatic patella osteomyelitis with MRSA infection and knee stiffness: a case report
Posttraumatic patella osteomyelitis is rare, and the treatment of osteomyelitis remains to be challenging. Control of the infection commonly costs a long time, and it is easily to cause knee stiffness. In addi...
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Open AccessTriptolide targets super-enhancer networks in pancreatic cancer cells and cancer-associated fibroblasts
The tumor microenvironment in pancreatic ductal adenocarcinoma (PDAC) is highly heterogeneous, fibrotic, and hypovascular, marked by extensive desmoplasia and maintained by the tumor cells, cancer-associated f...
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Open AccessEmergency retroperitoneal laparoscopic partial nephrectomy for ruptured renal angiomyolipomas: a retrospective single-center series of 15 cases
To assess the safety, tumor control and renal function preservation of the emergency retroperitoneal laparoscopic partial nephrectomy (LPN) for ruptured renal angiomyolipoma (AML) and summarize our single-cent...
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Open AccessUbiquitin ligase TRIM65 promotes colorectal cancer metastasis by targeting ARHGAP35 for protein degradation
Tripartite motif-containing protein 65 (TRIM65) is an E3 ubiquitin ligase and a critical regulator of a variety of cellular processes as well as tumor progression. Therefore, more substrates must be identified...
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Open AccessThe influences of anesthesia methods on some complications after orthopedic surgery: a Bayesian network meta-analysis
Although several anesthesia procedures have been explored for orthopedic surgery, the complications of anesthesia remain not well resolved. This study aimed to explore the influence of different anesthesia met...
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Open AccessSinew acupuncture for knee osteoarthritis: study protocol for a randomized sham-controlled trial
Sinew acupuncture is a new modality of acupuncture in which needles are inserted into acupoints, ashi points or spasm points of sinew and muscles along the meridian sinew pathway. A previous observational stud...
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Decitibine improve the efficiency of anti-PD-1 therapy via activating the response to IFN/PD-L1 signal of lung cancer cells
IFN-γ-induced PD-L1 expression represents the existence of tumor-specific T cells, which predicts high-response rate to anti-PD-1/L1 therapy, but loss-of-function of IFN signals (e.g., JAK mutation) induces ad...
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Open AccessCytocompatibility with osteogenic cells and enhanced in vivo anti-infection potential of quaternized chitosan-loaded titania nanotubes
Infection is one of the major causes of failure of orthopedic implants. Our previous study demonstrated that nanotube modification of the implant surface, together with nanotubes loaded with quaternized chitos...
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Uracil-DNA glycosylase (UNG) rs246079 G/A polymorphism is associated with decreased risk of esophageal cancer in a Chinese population
Esophageal cancer is the sixth leading cause of cancer-associated death worldwide. In addition to environmental risk factors, genetic factors might play an important role in esophageal cancer carcinogenesis. W...
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Genetic variations in MTHFR and esophageal squamous cell carcinoma susceptibility in Chinese Han population
Esophageal cancer is the sixth most common cancer worldwide. Esophageal squamous cell carcinoma (ESCC) is a fatal malignancy associated with low 5-year survival rate. The aim of this study was to assess the as...
