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Article

MPC1 deficiency accelerates lung adenocarcinoma progression through the STAT3 pathway

Mitochondrial pyruvate carrier 1 (MPC1), a key factor that controls pyruvate transportation in the mitochondria, is known to be frequently dysregulated in tumor initiation and progression. However, the clinica...

Hongbo Zou, Qian Chen, Anmei Zhang, Songtao Wang, Hong Wu, Ye Yuan… in Cell Death & Disease (2019)