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    Article

    Ochratoxin A (OTA) causes intestinal aging damage through the NLRP3 signaling pathway mediated by calcium overload and oxidative stress

    Ochratoxin A (OTA) is a widespread environmental toxin that poses a serious threat to human and animal health. OTA has been shown to cause cellular and tissue damage and is a global public health problem. Howe...

    Guoxia Wang, Shuai Zhang, Hainan Lan in Environmental Science and Pollution Resear… (2024)

  2. Article

    Open Access

    Long-term exposure to polystyrene microplastics triggers premature testicular aging

    Plastic pollution is greatly serious in the ocean and soil. Microplastics (MPs) degraded from plastic has threatened animals and humans health. The accumulation of MPs in the tissues and blood in animals and h...

    Deyi Wu, Meng Zhang, Ting Ting Bao, Hainan Lan in Particle and Fibre Toxicology (2023)

  3. Article

    Open Access

    Maternal effects drive intestinal development beginning in the embryonic period on the basis of maternal immune and microbial transfer in chickens

    Nutrition drives immunity and health in animals, and maternal immunity benefits offspring. In our previous study, a nutritional intervention strategy was found to promote the immunity of hens, which subsequent...

    Haizhou Gong, Tai** Wang, Min Wu, Qianran Chu, Hainan Lan, Wuying Lang in Microbiome (2023)

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    Article

    The Cellular Behavior, Intracellular Signaling Profile and Nuclear-Targeted Potential Functions of Porcine Growth Hormone (pGH) in Swine Testicular Cells

    Porcine growth hormone (pGH) has many important biological functions and roles, and the biological activity of pGH is closely related with its cell behavior and characteristics. However, so far, the behavior o...

    Yan Zhang, Qingrong Zhao, Deyi Wu, Shichun Li, Min Wu in Cell Biochemistry and Biophysics (2022)

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    Article

    The effect of heat stress on the cellular behavior, intracellular signaling profile of porcine growth hormone (pGH) in swine testicular cells

    At present, heat stress caused by the thermal environment is the main factor that endangers the reproductive function of animals. Growth hormone (GH) is a polypeptide hormone, the biological function of reprod...

    Yan Zhang, Qingrong Zhao, Deyi Wu, Hainan Lan in Cell Stress and Chaperones (2022)