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Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice

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  1. Article

    Open Access

    Direct effects of Bmi1 on p53 protein stability inactivates oncoprotein stress responses in embryonal cancer precursor cells at tumor initiation

    Embryonal cancer can arise from postnatally persistent embryonal remnant or rest cells, which are uniquely characterized by the absence of p53 mutations. Perinatal overexpression of the MycN oncoprotein in emb...

    M Calao, E O Sekyere, H J Cui, B B Cheung, W D Thomas, J Keating, J B Chen… in Oncogene (2013)

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