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    Chapter and Conference Paper

    Some Problems Concerning the Quantitative Assay of Primidone and Its Metabolites

    All pharmacokinetic studies dealing with primidone therapy are complicated because phenobarbitone and phenylethylmalondiamide (PEMA) are the main metabolites of the biotransformation of primidone.

    H. R. Schäfer in Clinical Pharmacology of Anti-Epileptic Drugs (1975)