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Chapter
Combined Use of wIRA and Microwave or Radiofrequency Hyperthermia
Clinical hyperthermia (i.e., heating of tumor tissue to 40–43 °C) is used in clinical oncology to enhance the therapeutic effect of chemotherapy and radiotherapy. Most recurrent breast cancer and melanoma lesi...
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Article
Open AccessAssessing the effect of hyperbaric oxygen therapy in breast cancer patients with late radiation toxicity (HONEY trial): a trial protocol using a trial within a cohort design
Breast cancer treatment with radiotherapy can induce late radiation toxicity, characterized by pain, fibrosis, edema, impaired arm mobility, and poor cosmetic outcome. Hyperbaric oxygen therapy (HBOT) has been...
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Article
Open AccessPatient-reported cosmetic satisfaction and the long-term association with quality of life in irradiated breast cancer patients
To evaluate patient-reported cosmetic satisfaction in women treated with radiation therapy for breast cancer and to determine the association between dissatisfaction and quality of life (QoL) and depression.
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Article
Open AccessThe effect of chemotherapy on subjective cognitive function in younger early-stage breast cancer survivors treated with chemotherapy compared to older patients
To evaluate the impact of chemotherapy on subjective cognitive functioning according to age in a large cohort of breast cancer patients.
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Article
Open AccessSevere depression more common in patients with ductal carcinoma in situ than early-stage invasive breast cancer patients
Ductal carcinoma in situ (DCIS) is associated with an excellent prognosis; historical studies have shown similar levels of psychological distress in patients with DCIS and with early-stage invasive breast canc...
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Article
Open AccessThe Utrecht cohort for Multiple BREast cancer intervention studies and Long-term evaLuAtion (UMBRELLA): objectives, design, and baseline results
In oncology, RCTs are often beset by slow recruitment, limited generalizability, and strong preferences for interventions by patients and physicians. The cohort multiple randomized controlled trial (cmRCT) is ...
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Article
Open AccessRedefining radiotherapy for early-stage breast cancer with single dose ablative treatment: a study protocol
A shift towards less burdening and more patient friendly treatments for breast cancer is currently ongoing. In low-risk patients with early-stage disease, accelerated partial breast irradiation (APBI) is an al...
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Article
Open AccessSentinel lymph node biopsy of the internal mammary chain in breast cancer
Routine removal of the internal mammary chain (IMC) sentinel node in breast cancer patients remains a subject of discussion. The aim of this study was to determine the impact of routinely performed IMC sentine...