11 Result(s)
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Chapter
Combined Use of wIRA and Microwave or Radiofrequency Hyperthermia
Clinical hyperthermia (i.e., heating of tumor tissue to 40–43 °C) is used in clinical oncology to enhance the therapeutic effect of chemotherapy and radiotherapy. Most recurrent breast cancer and melanoma lesi...
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Article
Open AccessAssessing the effect of hyperbaric oxygen therapy in breast cancer patients with late radiation toxicity (HONEY trial): a trial protocol using a trial within a cohort design
Breast cancer treatment with radiotherapy can induce late radiation toxicity, characterized by pain, fibrosis, edema, impaired arm mobility, and poor cosmetic outcome. Hyperbaric oxygen therapy (HBOT) has been...
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Article
Higher reconstruction failure and less patient-reported satisfaction after post mastectomy radiotherapy with immediate implant-based breast reconstruction compared to immediate autologous breast reconstruction
To improve shared decision making, clinical- and patient-reported outcomes between immediate implant-based and autologous breast reconstruction followed by postmastectomy radiotherapy (PMRT) were compared.
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Article
Open AccessPatient-reported cosmetic satisfaction and the long-term association with quality of life in irradiated breast cancer patients
To evaluate patient-reported cosmetic satisfaction in women treated with radiation therapy for breast cancer and to determine the association between dissatisfaction and quality of life (QoL) and depression.
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Open AccessThe effect of chemotherapy on subjective cognitive function in younger early-stage breast cancer survivors treated with chemotherapy compared to older patients
To evaluate the impact of chemotherapy on subjective cognitive functioning according to age in a large cohort of breast cancer patients.
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Open AccessSevere depression more common in patients with ductal carcinoma in situ than early-stage invasive breast cancer patients
Ductal carcinoma in situ (DCIS) is associated with an excellent prognosis; historical studies have shown similar levels of psychological distress in patients with DCIS and with early-stage invasive breast canc...
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Article
Open AccessThe Utrecht cohort for Multiple BREast cancer intervention studies and Long-term evaLuAtion (UMBRELLA): objectives, design, and baseline results
In oncology, RCTs are often beset by slow recruitment, limited generalizability, and strong preferences for interventions by patients and physicians. The cohort multiple randomized controlled trial (cmRCT) is ...
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Open AccessRedefining radiotherapy for early-stage breast cancer with single dose ablative treatment: a study protocol
A shift towards less burdening and more patient friendly treatments for breast cancer is currently ongoing. In low-risk patients with early-stage disease, accelerated partial breast irradiation (APBI) is an al...
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Article
Open AccessSentinel lymph node biopsy of the internal mammary chain in breast cancer
Routine removal of the internal mammary chain (IMC) sentinel node in breast cancer patients remains a subject of discussion. The aim of this study was to determine the impact of routinely performed IMC sentine...
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Article
Excised and irradiated volumes in relation to the tumor size in breast-conserving therapy
In early-stage breast cancer and DCIS patients, breast-conserving therapy is today’s standard of care. The purpose of this study was to evaluate the relation between the microscopic tumor diameter (mTD), the e...
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Article
Validated method for the determination of the novel organo-ruthenium anticancer drug NAMI-A in human biological fluids by Zeeman atomic absorption spectrometry
NAMI-A is a novel ruthenium-containing experimental anticancer agent. We have developed and validated a rapid and sensitive analytical method to determine NAMI-A in human plasma, plasma ultrafiltrate and urin...
