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Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both

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  1. Article

    Open Access

    Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status

    The multistep process of TP53 mutation expansion during myeloproliferative neoplasm (MPN) transformation into acute myeloid leukemia (AML) has been documented retrospectively. It is currently unknown how common T...

    B Kubesova, S Pavlova, J Malcikova, J Kabathova, L Radova, N Tom, B Tichy in Leukemia (2018)

  2. Article

    Erratum: A randomized study of pomalidomide vs placebo in persons with myeloproliferative neoplasm-associated myelofibrosis and RBC-transfusion dependence

    Correction to: Leukemia advance online publication 18 November 2016; doi:10.1038/leu.2016.300 Following the online publication of this article, the authors noted that Dr McMullin was incorrectly excluded from ...

    A Tefferi, H K Al-Ali, G Barosi, T Devos, H Gisslinger, Q Jiang, J-J Kiladjian in Leukemia (2017)

  3. Article

    Open Access

    A randomized study of pomalidomide vs placebo in persons with myeloproliferative neoplasm-associated myelofibrosis and RBC-transfusion dependence

    RBC-transfusion dependence is common in persons with myeloproliferative neoplasm (MPN)-associated myelofibrosis. The objective of this study was to determine the rates of RBC-transfusion independence after the...

    A Tefferi, H K Al-Ali, G Barosi, T Devos, H Gisslinger, Q Jiang, J-J Kiladjian in Leukemia (2017)

  4. Article

    Erratum: Long-term findings from COMFORT-II, a phase 3 study of ruxolitinib vs best available therapy for myelofibrosis

    Correction to: Leukemia (2016) 30, 1701–1707; doi:10.1038/leu.2016.148 Following the publication of this article the authors noted that the IPSS risk assignment was incorrectly listed in the second paragraph o...

    C N Harrison, A M Vannucchi, J-J Kiladjian, H K Al-Ali, H Gisslinger, L Knoops in Leukemia (2017)

  5. Article

    Open Access

    Response to Harrison et al. ‘Clinically relevant differences between BCSH and WHO diagnostic criteria for ET’

    H Gisslinger, G Jeryczynski, A Wölfler, C Beham-Schmid, J Thiele in Leukemia (2017)

  6. Article

    Erratum: Clinical impact of bone marrow morphology for the diagnosis of essential thrombocythemia: comparison between the BCSH and the WHO criteria

    Correction to: Leukemia (2016) 30, 1126–1132; doi:10.1038/leu.2015.360 Following the publication of this Article, the authors noted that there were errors in Tables 2 and 4. The correct tables are provided bel...

    H Gisslinger, G Jeryczynski, B Gisslinger, A Wölfler, S Burgstaller in Leukemia (2017)

  7. Article

    Open Access

    Long-term findings from COMFORT-II, a phase 3 study of ruxolitinib vs best available therapy for myelofibrosis

    Ruxolitinib is a Janus kinase (JAK) (JAK1/JAK2) inhibitor that has demonstrated superiority over placebo and best available therapy (BAT) in the Controlled Myelofibrosis Study with Oral JAK Inhibitor Treatment...

    C N Harrison, A M Vannucchi, J-J Kiladjian, H K Al-Ali, H Gisslinger, L Knoops in Leukemia (2016)

  8. Article

    Open Access

    Clinical impact of bone marrow morphology for the diagnosis of essential thrombocythemia: comparison between the BCSH and the WHO criteria

    Essential thrombocythemia (ET) is currently diagnosed either by the British Committee of Standards in Haematology (BCSH) criteria that are predominantly based on exclusion and not necessarily on bone marrow (B...

    H Gisslinger, G Jeryczynski, B Gisslinger, A Wölfler, S Burgstaller in Leukemia (2016)

  9. Article

    Open Access

    Practice-relevant revision of IPSET-thrombosis based on 1019 patients with WHO-defined essential thrombocythemia

    T Barbui, A M Vannucchi, V Buxhofer-Ausch, V De Stefano, S Betti in Blood Cancer Journal (2015)

  10. Article

    Open Access

    Allelic imbalance in CALR somatic mutagenesis

    A S Harutyunyan, R Jäger, D Chen, T Berg, E Rumi, B Gisslinger, D Pietra in Leukemia (2015)

  11. Article

    Open Access

    Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study

    Under the auspices of an International Working Group, seven centers submitted diagnostic and follow-up information on 1545 patients with World Health Organization-defined polycythemia vera (PV). At diagnosis, ...

    A Tefferi, E Rumi, G Finazzi, H Gisslinger, A M Vannucchi, F Rodeghiero in Leukemia (2013)

  12. Article

    Open Access

    Mutations with epigenetic effects in myeloproliferative neoplasms and recent progress in treatment: Proceedings from the 5th International Post-ASH Symposium

    Immediately following the 2010 annual American Society of Hematology (ASH) meeting, the 5th International Post-ASH Symposium on Chronic Myelogenous Leukemia and BCR-ABL1-Negative Myeloproliferative Neoplasms (MPN...

    A Tefferi, O Abdel-Wahab, F Cervantes, J D Crispino, G Finazzi in Blood Cancer Journal (2011)

  13. Article

    Erratum: A unified definition of clinical resistance/intolerance to hydroxyurea in essential thrombocythemia: results of a consensus process by an international working group

    Correction to: Leukemia (2007) 21, 277–280. doi:10.1038/sj.leu.2404473 It has been identified by the authors that there is an error in Table 2. The correct Table 2 is shown below: The authors apologize for any...

    G Barosi, C Besses, G Birgegard, J Briere, F Cervantes, G Finazzi, H Gisslinger in Leukemia (2007)