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Article
The neuronal and extraneuronal uptake and deamination of 3H-(−)-phenylephrine in the perfused rat heart
The neuronal and extraneuronal uptake and deamination of 3H-(−)-phenylephrine was studied in perfused rat hearts obtained from reserpine-pretreated animals.
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Article
The positive inotropic effect of (−)-noradrenaline and (±)-isoprenaline after chemical sympathectomy: Evidence in favour of differences at a postsynaptic site
The positive inotropic effects of (−)-noradrenaline and (±)-isoprenaline were studied on guinea-pig papillary muscles after chemical sympathectomy with 6-hydroxydopamine.
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Article
A comparative study of the properties of the catechol-O-methyltransferase inhibitors, U-0521 and tropolone acetamide, in rat perfused heart
The properties of two inhibitors of catechol-O-methyltransferase (COMT), U-0521 and tropolone acetamide, were compared in rat hearts perfused with3H-isoprenaline.
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Article
The extraneuronal compartments for the distribution of isoprenaline in the rat heart
The distribution of 3H-isoprenaline in the perfused rat heart was re-examined. After initial loading with 3H-isoprenaline hearts were washed out with amine-free solution; the efflux curves were subjected to the p...
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Die Entwicklung gesetzlicher Bestimmungen in der industriellen Toxikologie
In ihrem zeitlichen Ablauf wurde die Entwicklung der gesetzlichen Regulierungen in der industriellen Toxikologie durch verschiedene Grundprinzipien bestimmt. Gesetze können nur den jeweiligen Stand der wissens...