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Article
Open AccessReduced bone mineral density in adolescents with Duchenne Muscular Dystrophy (DMD) and scoliosis
Duchenne muscular dystrophy is a progressive disease usually associated with loss of ambulation and progressive scoliosis. Immobilisation and glucocorticoid treatment are predisposing factors for reduced bone...
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Article
Open AccessTitanium wear from magnetically controlled growing rods (MCGRs) for the treatment of spinal deformities in children
Magnetically controlled growing rods (MCGRs) are an effective treatment method for early-onset scoliosis (EOS). In recent years, increasing titanium wear was observed in tissue adjacent to implants and in bloo...
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Article
Rituximab in routine care of severe active rheumatoid arthritis
To assess safety, effectiveness and onset of effect of rituximab (RTX) in routine clinical treatment of severe, active rheumatoid arthritis (RA).
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Article
Open AccessFamilial chilblain lupus caused by an activating mutation in STING
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Article
Open AccessAnti-IL1 therapy in patients with refractory FMF living inGermany
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Article
Open AccessPW03-029 – Risk factors for AA-type amyloidosis in Germany
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Article
Patients with active rheumatoid arthritis but only few tender and swollen joints: a subgroup with impaired short term outcome
The disease activity score of 28 joints (DAS28) is now commonly used for the guidance of treatment decisions in rheumatoid arthritis (RA). The goal of this work was to determine whether patients with DAS28 > 3...
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Article
Autoantigens are translocated into small apoptotic bodies during early stages of apoptosis
A dysregulation of apoptosis or an ineffective clearance of apoptotic material is suspected to be involved in the pathogenesis of systemic lupus erythematodes. Subcellular fragments such as apoptotic bodies (A...
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Article
Rapid progressive eosinophilic cardiomyopathy in a patient with Churg–Strauss syndrome (CSS)
Churg–Strauss syndrome (CSS) is a rare necrotizing, systemic vasculitis that is almost invariably associated with bronchial asthma. Although overall prognosis is good and treatment with corticosteroids alone o...
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Article
Induction of apoptosis by spermine-metabolites in primary human blood cells and various tumor cell lines
Polyamines are involved in the regulation of cellular growth and survival by interacting with processes like translation, transcription or ion transport. The aim of our study was to analyze whether polyamines ...
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Article
Induction of apoptosis by polyamine metabolites in immunocompetent cells and different tumor cell lines
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Article
Role of apoptosis in autoimmunity
Apoptosis is a physiological form of cell death required to ensure that the rate of cell division is balanced by the rate of cell death in multicellular organisms. Dysregulation of apoptosis is associated with...
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Article
CD 95-independent mechanisms of IL-2 deprivation-induced apoptosis in activated human lymphocytes
Growth factor deprivation-induced apoptosis plays an important role in several cellular systems. However, knowledge of the molecular mechanisms involved are restricted to a few murine models or tumor cell line...
