-
Article
Open AccessLabel-free multiphoton microscopy enables histopathological assessment of colorectal liver metastases and supports automated classification of neoplastic tissue
As the state of resection margins is an important prognostic factor after extirpation of colorectal liver metastases, surgeons aim to obtain negative margins, sometimes elaborated by resections of the positive...
-
Article
Open AccessIntegrated radiogenomics analyses allow for subtype classification and improved outcome prognosis of patients with locally advanced HNSCC
Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) may benefit from personalised treatment, requiring biomarkers that characterize the tumour and predict treatment response. We integr...
-
Article
Open AccessNRP2 transcriptionally regulates its downstream effector WDFY1
Neuropilins (NRPs) are cell surface glycoproteins that often act as co-receptors for plexins and VEGF family receptors. Neuropilin-2 (NRP2), a family member of NRPs, was shown to regulate autophagy and endocyt...
-
Article
Open AccessLee mortality index as comorbidity measure in patients undergoing radical cystectomy
To investigate the recently described Lee mortality index as predictor of mortality after radical cystectomy.