3 Result(s)
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Article
Open AccessStandardized and quality-assured predictive PD-L1 testing in the upper gastrointestinal tract
As a result of the high approval dynamics and the growing number of immuno-oncological concepts, the complexity of treatment decisions and control in the area of cancers of the esophagus, gastroesophageal junc...
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Article
Open AccessCharacterization and evaluation of gene fusions as a measure of genetic instability and disease prognosis in prostate cancer
Prostate cancer (PCa) is one of the most prevalent cancers worldwide. The clinical manifestations and molecular characteristics of PCa are highly variable. Aggressive types require radical treatment, whereas i...
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Article
Open AccessDickkopf-1 is regulated by the mevalonate pathway in breast cancer
Amino-bisphosphonates and statins inhibit the mevalonate pathway, and may exert anti-tumor effects. The Wnt inhibitor dickkopf-1 (DKK-1) promotes osteolytic bone lesions by inhibiting osteoblast functions and ...
