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    Open Access

    Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones

    Many reagents have been developed for cysteine-specific protein modification. However, few of them allow for multi-functionalization of a single Cys residue and disulfide bridging bioconjugation. Herein, we re...

    Yingqian Zhang, Chuanlong Zang, Guoce An, Mengdi Shang… in Nature Communications (2020)

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